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1.
A novel and translational role for autophagy in antisense oligonucleotide trafficking and activity.
Nucleic Acids Res
; 47(21): 11284-11303, 2019 12 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31612951
2.
Enhanced Potency of GalNAc-Conjugated Antisense Oligonucleotides in Hepatocellular Cancer Models.
Mol Ther
; 27(9): 1547-1557, 2019 09 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31303442
3.
Metabolism and Disposition of Volanesorsen, a 2'-O-(2 methoxyethyl) Antisense Oligonucleotide, Across Species.
Drug Metab Dispos
; 47(10): 1164-1173, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31350288
4.
Comparison of the Class Effects of Antisense Oligonucleotides in CByB6F1-Tg(HRAS)2Jic and CD-1 Mice.
Toxicol Pathol
; 47(1): 82-92, 2019 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30585133
5.
2022 White Paper on Recent Issues in Bioanalysis: ICH M10 BMV Guideline & Global Harmonization; Hybrid Assays; Oligonucleotides & ADC; Non-Liquid & Rare Matrices; Regulatory Inputs (Part 1A - Recommendations on Mass Spectrometry, Chromatography and Sample Preparation, Novel Technologies, Novel Modalities, and Novel Challenges, ICH M10 BMV Guideline & Global Harmonization Part 1B - Regulatory Agencies' Inputs on Regulated Bioanalysis/BMV, Biomarkers/CDx/BAV, Immunogenicity, Gene & Cell Therapy and Vaccine).
Bioanalysis
; 15(16): 955-1016, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37650500
6.
2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH M10 Section 7.1; Non-Liquid & Rare Matrices; Regulatory Inputs (Part 1A - Recommendations on Endogenous Compounds, Small Molecules, Complex Methods, Regulated Mass Spec of Large Molecules, Small Molecule, PoC & Part 1B - Regulatory Agencies' Inputs on Bioanalysis, Biomarkers, Immunogenicity, Gene & Cell Therapy and Vaccine).
Bioanalysis
; 14(9): 505-580, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35578993
7.
Txnip balances metabolic and growth signaling via PTEN disulfide reduction.
Proc Natl Acad Sci U S A
; 105(10): 3921-6, 2008 Mar 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-18322014
8.
2020 White Paper on Recent Issues in Bioanalysis: BMV of Hybrid Assays, Acoustic MS, HRMS, Data Integrity, Endogenous Compounds, Microsampling and Microbiome (Part 1 - Recommendations on Industry/Regulators Consensus on BMV of Biotherapeutics by LCMS, Advanced Application in Hybrid Assays, Regulatory Challenges in Mass Spec, Innovation in Small Molecules, Peptides and Oligos).
Bioanalysis
; 13(4): 203-238, 2021 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-33470871
9.
Co-Administration of an Excipient Oligonucleotide Helps Delineate Pathways of Productive and Nonproductive Uptake of Phosphorothioate Antisense Oligonucleotides in the Liver.
Nucleic Acid Ther
; 27(4): 209-220, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-28448194
10.
Assessment of the Drug Interaction Potential of Unconjugated and GalNAc3-Conjugated 2'-MOE-ASOs.
Mol Ther Nucleic Acids
; 9: 34-47, 2017 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29246313
11.
Disposition and Pharmacology of a GalNAc3-conjugated ASO Targeting Human Lipoprotein (a) in Mice.
Mol Ther Nucleic Acids
; 5: e317, 2016 May 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27138177
12.
Elucidation of the Biotransformation Pathways of a Galnac3-conjugated Antisense Oligonucleotide in Rats and Monkeys.
Mol Ther Nucleic Acids
; 5: e319, 2016 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27164023
13.
Disposition and Pharmacokinetics of a GalNAc3-Conjugated Antisense Oligonucleotide Targeting Human Lipoprotein (a) in Monkeys.
Nucleic Acid Ther
; 26(6): 372-380, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27500733
14.
Bioanalysis considerations on the pharmacokinetic evaluation of antisense therapeutics.
Bioanalysis
; 11(21): 1909-1912, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-31648523
15.
Validation and application of a liquid chromatography-tandem mass spectrometric method for the simultaneous determination of testosterone and dihydrotestosterone in rat prostatic tissue using a 96-well format.
J Chromatogr B Analyt Technol Biomed Life Sci
; 877(29): 3515-21, 2009 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19767251
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