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1.
Guanylyl cyclase-A phosphorylation decreases cardiac hypertrophy and improves systolic function in male, but not female, mice.
FASEB J
; 36(1): e22069, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34859913
2.
Guanylyl Cyclase-B Dependent Bone Formation in Mice is Associated with Youth, Increased Osteoblasts, and Decreased Osteoclasts.
Calcif Tissue Int
; 111(5): 506-518, 2022 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-35947145
3.
Regulation of the Natriuretic Peptide Receptor 2 (Npr2) by Phosphorylation of Juxtamembrane Serine and Threonine Residues Is Essential for Bifurcation of Sensory Axons.
J Neurosci
; 38(45): 9768-9780, 2018 11 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30249793
4.
Skeletal overgrowth-causing mutations mimic an allosterically activated conformation of guanylyl cyclase-B that is inhibited by 2,4,6,-trinitrophenyl ATP.
J Biol Chem
; 292(24): 10220-10229, 2017 06 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-28450398
5.
A Glutamate-Substituted Mutant Mimics the Phosphorylated and Active Form of Guanylyl Cyclase-A.
Mol Pharmacol
; 92(1): 67-74, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28416574
6.
Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone.
Dev Biol
; 409(1): 194-201, 2016 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26522847
7.
Catalytically Active Guanylyl Cyclase B Requires Endoplasmic Reticulum-mediated Glycosylation, and Mutations That Inhibit This Process Cause Dwarfism.
J Biol Chem
; 291(21): 11385-93, 2016 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-26980729
8.
Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytes.
Development
; 141(18): 3594-604, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25183874
9.
Cyclic AMP links luteinizing hormone signaling to dephosphorylation and inactivation of the NPR2 guanylyl cyclase in ovarian follicles.
Biol Reprod
; 104(5): 939-941, 2021 05 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33624759
10.
Heterozygous mutations in natriuretic peptide receptor-B (NPR2) gene as a cause of short stature.
Hum Mutat
; 36(4): 474-81, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25703509
11.
Phosphorylation-Dependent Regulation of Guanylyl Cyclase (GC)-A and Other Membrane GC Receptors.
Endocr Rev
; 2024 May 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38713083
12.
Luteinizing hormone reduces the activity of the NPR2 guanylyl cyclase in mouse ovarian follicles, contributing to the cyclic GMP decrease that promotes resumption of meiosis in oocytes.
Dev Biol
; 366(2): 308-16, 2012 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22546688
13.
Novel enhancers of guanylyl cyclase-A activity acting via allosteric modulation.
Br J Pharmacol
; 180(24): 3254-3270, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37522273
14.
The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors.
Br J Pharmacol
; 180 Suppl 2: S241-S288, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-38123155
15.
Guanylyl cyclase (GC)-A and GC-B activities in ventricles and cardiomyocytes from failed and non-failed human hearts: GC-A is inactive in the failed cardiomyocyte.
J Mol Cell Cardiol
; 52(3): 727-32, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22133375
16.
ATP potentiates competitive inhibition of guanylyl cyclase A and B by the staurosporine analog, Gö6976: reciprocal regulation of ATP and GTP binding.
J Biol Chem
; 286(39): 33841-4, 2011 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-21828054
17.
Insulin-degrading enzyme modulates the natriuretic peptide-mediated signaling response.
J Biol Chem
; 286(6): 4670-9, 2011 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-21098034
18.
Biodesign of a renal-protective peptide based on alternative splicing of B-type natriuretic peptide.
Proc Natl Acad Sci U S A
; 106(27): 11282-7, 2009 Jul 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-19541613
19.
Vicinal glutamates are better phosphomimetics: Phosphorylation is required for allosteric activation of guanylyl cyclase-A.
Front Mol Neurosci
; 15: 1012784, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36407758
20.
Epitope-tagged and phosphomimetic mouse models for investigating natriuretic peptide-stimulated receptor guanylyl cyclases.
Front Mol Neurosci
; 15: 1007026, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36340689