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1.
Prophylactic use of an anti-activated factor XII monoclonal antibody, garadacimab, for patients with C1-esterase inhibitor-deficient hereditary angioedema: a randomised, double-blind, placebo-controlled, phase 2 trial.
Lancet
; 399(10328): 945-955, 2022 03 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35219377
2.
Prophylactic therapy with subcutaneous C1-inhibitor is associated with sustained symptom control in patients with hereditary angioedema.
Allergy Asthma Proc
; 43(3): 202-208, 2022 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35524357
3.
Prevention of Hereditary Angioedema Attacks with a Subcutaneous C1 Inhibitor.
N Engl J Med
; 376(12): 1131-1140, 2017 03 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-28328347
4.
Long-term safety and efficacy of subcutaneous C1-inhibitor in older patients with hereditary angioedema.
Ann Allergy Asthma Immunol
; 125(3): 334-340.e1, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32445670
5.
FXIIa inhibitor rHA-Infestin-4: Safe thromboprotection in experimental venous, arterial and foreign surface-induced thrombosis.
Br J Haematol
; 173(5): 769-78, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27018425
6.
Reconstituted high-density lipoprotein can elevate plasma alanine aminotransferase by transient depletion of hepatic cholesterol: role of the phospholipid component.
J Appl Toxicol
; 36(8): 1038-47, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26651060
7.
Effective reversal of edoxaban-associated bleeding with four-factor prothrombin complex concentrate in a rabbit model of acute hemorrhage.
Anesthesiology
; 122(2): 387-98, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25419685
8.
Novel formulation of a reconstituted high-density lipoprotein (CSL112) dramatically enhances ABCA1-dependent cholesterol efflux.
Arterioscler Thromb Vasc Biol
; 33(9): 2202-11, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23868939
9.
Garadacimab for hereditary angioedema attack prevention: long-term efficacy, quality of life, and safety data from a phase 2, randomised, open-label extension study.
Lancet Haematol
; 11(6): e436-e447, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38710185
10.
Medetomidine/midazolam/ketamine anaesthesia in ferrets: effects on cardiorespiratory parameters and evaluation of plasma drug concentrations.
Vet Anaesth Analg
; 38(5): 439-50, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21831049
11.
Evaluation of the prothrombotic potential of four-factor prothrombin complex concentrate (4F-PCC) in animal models.
PLoS One
; 16(10): e0258192, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34614035
12.
Long-Term Efficacy of Subcutaneous C1 Inhibitor in Pediatric Patients with Hereditary Angioedema.
Pediatr Allergy Immunol Pulmonol
; 33(3): 136-141, 2020 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32953229
13.
Long-term efficacy and safety of subcutaneous C1-inhibitor in women with hereditary angioedema: subgroup analysis from an open-label extension of a phase 3 trial.
Allergy Asthma Clin Immunol
; 16: 8, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32042283
14.
Subcutaneous C1 inhibitor for prevention of attacks of hereditary angioedema: additional outcomes and subgroup analysis of a placebo-controlled randomized study.
Allergy Asthma Clin Immunol
; 15: 49, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31485239
15.
Long-Term Outcomes with Subcutaneous C1-Inhibitor Replacement Therapy for Prevention of Hereditary Angioedema Attacks.
J Allergy Clin Immunol Pract
; 7(6): 1793-1802.e2, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30772477
16.
Exposure-Response Model of Subcutaneous C1-Inhibitor Concentrate to Estimate the Risk of Attacks in Patients With Hereditary Angioedema.
CPT Pharmacometrics Syst Pharmacol
; 7(3): 158-165, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29316335
17.
Health-Related Quality of Life with Subcutaneous C1-Inhibitor for Prevention of Attacks of Hereditary Angioedema.
J Allergy Clin Immunol Pract
; 6(5): 1733-1741.e3, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29391286
18.
The Coagulation Factor XIIa Inhibitor rHA-Infestin-4 Improves Outcome after Cerebral Ischemia/Reperfusion Injury in Rats.
PLoS One
; 11(1): e0146783, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26815580
19.
Effects of Continuous Plasma-Derived Subcutaneous C1-Esterase Inhibitor on Coagulation and Fibrinolytic Parameters.
Thromb Haemost
; 121(5): 690-693, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33202446
20.
Utility of a high VWF: FVIII ratio in preventing FVIII accumulation: a study in VWF-deficient mice.
Blood Coagul Fibrinolysis
; 26(5): 515-21, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25767894