Detalles de la búsqueda
1.
Novel Derivatives of Eugenol as a New Class of PPARγ Agonists in Treating Inflammation: Design, Synthesis, SAR Analysis and In Vitro Anti-Inflammatory Activity.
Molecules
; 28(9)2023 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37175309
2.
Biphenyl-based small molecule inhibitors: Novel cancer immunotherapeutic agents targeting PD-1/PD-L1 interaction.
Bioorg Med Chem
; 73: 117001, 2022 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36126447
3.
Design, parallel synthesis of Biginelli 1,4-dihydropyrimidines using PTSA as a catalyst, evaluation of anticancer activity and structure activity relationships via 3D QSAR studies.
Bioorg Chem
; 117: 105462, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34753059
4.
Structure-based design and synthesis of new 4-methylcoumarin-based lignans as pro-inflammatory cytokines (TNF-α, IL-6 and IL-1ß) inhibitors.
Bioorg Chem
; 89: 102991, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31153100
5.
Thiazolidinediones as antidiabetic agents: A critical review.
Bioorg Chem
; 77: 548-567, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29475164
6.
Design, synthesis and glucose uptake activity of some novel glitazones.
Bioorg Chem
; 56: 27-33, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24927033
7.
Discovery of novel glitazones incorporated with phenylalanine and tyrosine: synthesis, antidiabetic activity and structure-activity relationships.
Bioorg Chem
; 45: 12-28, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23064124
8.
Novel dual PPARα/γ agonists protect against liver steatosis and improve insulin sensitivity while avoiding side effects.
Eur J Pharmacol
; 935: 175322, 2022 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36228743
9.
Novel derivatives of eugenol as potent anti-inflammatory agents via PPARγ agonism: rational design, synthesis, analysis, PPARγ protein binding assay and computational studies.
RSC Adv
; 12(26): 16966-16978, 2022 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35754905
10.
A promising in silico protocol to develop novel PPARγ antagonists as potential anticancer agents: Design, synthesis and experimental validation via PPARγ protein activity and competitive binding assay.
Comput Biol Chem
; 95: 107600, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34794076
11.
Minutes of PPAR-γ agonism and neuroprotection.
Neurochem Int
; 140: 104814, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32758586
12.
Two Rationally Identified Novel Glitazones Reversed the Behavioral Dysfunctions and Exhibited Neuroprotection Through Ameliorating Brain Cytokines and Oxy-Radicals in ICV-LPS Neuroinflammatory Rat Model.
Front Neurosci
; 14: 530148, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33100954
13.
Rational Design, Synthesis, and In Vitro Neuroprotective Evaluation of Novel Glitazones for PGC-1α Activation via PPAR-γ: a New Therapeutic Strategy for Neurodegenerative Disorders.
Neurotox Res
; 37(3): 508-524, 2020 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-31782098
14.
Predicting anti-HIV activity of 1,3,4-thiazolidinone derivatives: 3D-QSAR approach.
Eur J Med Chem
; 44(3): 1180-7, 2009 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-18687505
15.
Novel Biginelli dihydropyrimidines with potential anticancer activity: a parallel synthesis and CoMSIA study.
Eur J Med Chem
; 44(10): 4192-8, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19525040
16.
QSAR Study on Thiazolidine-2,4-dione Derivatives for Antihyperglycemic Activity.
Indian J Pharm Sci
; 70(5): 565-71, 2008 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21394250
Resultados
1 -
16
de 16
1
Próxima >
>>