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1.
Neural functional connectivity changes to psychosocial stress in young adults with bipolar disorder and preliminary associations with clinical trajectories.
Bipolar Disord
; 24(3): 298-309, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34532945
2.
Use of Quality Improvement Strategies Among Small to Medium-Size US Primary Care Practices.
Ann Fam Med
; 16(Suppl 1): S35-S43, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29632224
3.
Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitors.
Bioorg Med Chem Lett
; 26(19): 4606-4612, 2016 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27578246
4.
Design and Characterization of 1,3-Dihydro-2H-benzo[d]azepin-2-ones as Rule-of-5 Compliant Bivalent BET Inhibitors.
ACS Med Chem Lett
; 14(9): 1231-1236, 2023 Sep 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37736196
5.
Design, Synthesis, and Characterization of I-BET567, a Pan-Bromodomain and Extra Terminal (BET) Bromodomain Oral Candidate.
J Med Chem
; 65(3): 2262-2287, 2022 02 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34995458
6.
HIV-1 and microvesicles from T cells share a common glycome, arguing for a common origin.
Nat Chem Biol
; 5(4): 244-50, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19234452
7.
Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor.
Bioorg Med Chem Lett
; 21(20): 6188-94, 2011 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21903390
8.
Optimization of a Series of 2,3-Dihydrobenzofurans as Highly Potent, Second Bromodomain (BD2)-Selective, Bromo and Extra-Terminal Domain (BET) Inhibitors.
J Med Chem
; 64(15): 10711-10741, 2021 08 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34260229
9.
Identification of a Series of N-Methylpyridine-2-carboxamides as Potent and Selective Inhibitors of the Second Bromodomain (BD2) of the Bromo and Extra Terminal Domain (BET) Proteins.
J Med Chem
; 64(15): 10742-10771, 2021 08 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34232650
10.
Discovery of a Highly Selective BET BD2 Inhibitor from a DNA-Encoded Library Technology Screening Hit.
J Med Chem
; 64(15): 10806-10833, 2021 08 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34251219
11.
Template-Hopping Approach Leads to Potent, Selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2) Inhibitors.
J Med Chem
; 64(6): 3249-3281, 2021 03 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-33662213
12.
Fragment-based Scaffold Hopping: Identification of Potent, Selective, and Highly Soluble Bromo and Extra Terminal Domain (BET) Second Bromodomain (BD2) Inhibitors.
J Med Chem
; 64(15): 10772-10805, 2021 08 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34255512
13.
Design and Synthesis of a Highly Selective and In Vivo-Capable Inhibitor of the Second Bromodomain of the Bromodomain and Extra Terminal Domain Family of Proteins.
J Med Chem
; 63(17): 9070-9092, 2020 09 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32691591
14.
GSK973 Is an Inhibitor of the Second Bromodomains (BD2s) of the Bromodomain and Extra-Terminal (BET) Family.
ACS Med Chem Lett
; 11(8): 1581-1587, 2020 Aug 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-32832027
15.
The Optimization of a Novel, Weak Bromo and Extra Terminal Domain (BET) Bromodomain Fragment Ligand to a Potent and Selective Second Bromodomain (BD2) Inhibitor.
J Med Chem
; 63(17): 9093-9126, 2020 09 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32702236
16.
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.
Science
; 368(6489): 387-394, 2020 04 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-32193360
17.
Quinolines as a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administration.
Bioorg Med Chem Lett
; 19(5): 1380-5, 2009 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19195882
18.
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives.
J Med Chem
; 59(4): 1370-87, 2016 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-26771203
19.
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.
J Med Chem
; 59(4): 1357-69, 2016 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-26771107
20.
The physiology of the normal human breast: an exploratory study.
J Physiol Biochem
; 67(4): 621-7, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21983803