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1.
Thienopyridine ureas as dual inhibitors of the VEGF and Aurora kinase families.
Bioorg Med Chem Lett
; 22(9): 3208-12, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22465635
2.
Cardiovascular effects of torcetrapib in conscious and pentobarbital-anesthetized dogs.
J Cardiovasc Pharmacol
; 54(6): 543-51, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19770671
3.
Discovery of ((4R,5S)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
J Med Chem
; 49(22): 6439-42, 2006 Nov 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-17064063
4.
Screening for cardiovascular safety: a structure-activity approach for guiding lead selection of melanin concentrating hormone receptor 1 antagonists.
J Med Chem
; 49(7): 2339-52, 2006 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-16570930
5.
Optimization of chromone-2-carboxamide melanin concentrating hormone receptor 1 antagonists: assessment of potency, efficacy, and cardiovascular safety.
J Med Chem
; 49(22): 6569-84, 2006 Nov 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-17064075
6.
Discovery and characterization of aminopiperidinecoumarin melanin concentrating hormone receptor 1 antagonists.
J Med Chem
; 48(19): 5888-91, 2005 Sep 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-16161992
7.
Comparative effects of levosimendan, OR-1896, OR-1855, dobutamine, and milrinone on vascular resistance, indexes of cardiac function, and O2 consumption in dogs.
Am J Physiol Heart Circ Physiol
; 294(1): H238-48, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17982006
8.
Effects of intravenous ABT-870 (iron (III)-hydroxide oligosaccharide) on mean arterial pressure and heart rate in the anaesthetized beagle: comparison with other iron-containing haematinic agents.
Clin Exp Pharmacol Physiol
; 32(12): 1020-6, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16445566
9.
Pharmacological characterization of the novel dihydropyridine potassium channel opener, (9R)-9-(3-iodo-4-methylphenyl)-5,9-dihydro-3H-furo[3,4-b]pyrano[4,3-e]pyridine-1,8(4H,7H)-dione (A-325100), and the regulation of cardiovascular function in conscious and anesthetized beagle dogs.
J Cardiovasc Pharmacol
; 46(2): 232-40, 2005 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16044036
10.
Hypertension induced by blockade of ET(B) receptors in conscious nonhuman primates: role of ET(A) receptors.
Am J Physiol Heart Circ Physiol
; 283(4): H1555-61, 2002 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-12234809
11.
(-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637), a novel ATP-sensitive potassium channel opener: hemodynamic comparison to ZD-6169, WAY-133537, and nifedipine in the anesthetized canine.
J Cardiovasc Pharmacol
; 44(2): 137-47, 2004 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15243293
12.
ABT-089: pharmacological properties of a neuronal nicotinic acetylcholine receptor agonist for the potential treatment of cognitive disorders.
CNS Drug Rev
; 10(2): 167-82, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15179445
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