Detalles de la búsqueda
1.
New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor.
Trends Pharmacol Sci
; 19(11): 467-75, 1998 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-9850611
2.
Design and synthesis of some substrate analogue inhibitors of phospholipase A2 and investigations by NMR and molecular modeling into the binding interactions in the enzyme-inhibitor complex.
J Med Chem
; 35(16): 2939-51, 1992 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-1501221
3.
Changes in the structure of bovine phospholipase A2 upon micelle binding.
Biochem J
; 305 ( Pt 3): 935-44, 1995 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-7848295
4.
2-Hydroxyethyl-alpha-D-glucopyranoside-2,3',4'-trisphosphate, a novel, metabolically resistant, adenophostin A and myo-inositol-1,4,5-trisphosphate analogue, potently interacts with the myo-inositol-1,4,5-trisphosphate receptor.
Mol Pharmacol
; 47(6): 1204-11, 1995 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-7603461
5.
Effect of replacement of ferriprotoporphyrin IX in the haem domain of cytochrome P-450 BM-3 on substrate binding and catalytic activity.
Biochem J
; 310 ( Pt 3): 939-43, 1995 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-7575430
6.
Equilibrium and kinetic studies of substrate binding to 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Escherichia coli.
J Biol Chem
; 275(24): 17962-7, 2000 Jun 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-10751386
7.
Engineering the substrate specificity of Bacillus megaterium cytochrome P-450 BM3: hydroxylation of alkyl trimethylammonium compounds.
Biochem J
; 327 ( Pt 2): 537-44, 1997 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-9359427
8.
13C NMR study of the ionizations within a trypsin-chloromethyl ketone inhibitor complex.
Biochemistry
; 24(14): 3478-87, 1985 Jul 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-4041423
9.
A 13C-n.m.r. investigation of ionizations within a trypsin-inhibitor complex. Evidence that the pKa of histidine-57 is raised by interaction with the hemiketal oxyanion.
Biochem J
; 231(3): 677-82, 1985 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-4074329
10.
NMR studies of substrate binding to cytochrome P450 BM3: comparisons to cytochrome P450 cam.
Biochemistry
; 34(28): 8982-8, 1995 Jul 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-7619797
11.
1H NMR studies of bovine and porcine phospholipase A2: assignment of aromatic resonances and evidence for a conformational equilibrium in solution.
Biochemistry
; 28(14): 5939-46, 1989 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-2775744
12.
A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation.
Biochemistry
; 36(7): 1567-72, 1997 Feb 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-9048540
13.
The binding of amide substrate analogues to phospholipase A2. Studies by 13C-nuclear-magnetic-resonance and infrared spectroscopy.
Biochem J
; 288 ( Pt 1): 167-73, 1992 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-1445261
14.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as a substrate of cytochrome P450 2D6: allosteric effects of NADPH-cytochrome P450 reductase.
Biochemistry
; 36(15): 4461-70, 1997 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-9109653
15.
Crystallization and preliminary X-ray diffraction studies of human cytochrome P450 reductase.
J Struct Biol
; 116(2): 320-5, 1996.
Artículo
en Inglés
| MEDLINE | ID: mdl-8812989
16.
A model for human cytochrome P450 2D6 based on homology modeling and NMR studies of substrate binding.
Biochemistry
; 35(14): 4540-50, 1996 Apr 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-8605204
17.
The catalytic mechanism of cytochrome P450 BM3 involves a 6 A movement of the bound substrate on reduction.
Nat Struct Biol
; 3(5): 414-7, 1996 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-8612070
18.
2-Hydroxyethyl alpha-D-glucopyranoside 2,3',4'-trisphosphate: a novel metabolically resistant adenophostin A and myo-inositol 1,4,5-trisphosphate analogue potently interacts with the myo-inositol 1,4,5-trisphosphate receptor.
Biochem Soc Trans
; 23(3): 420S, 1995 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-8566308
19.
Redox cycling by cytochrome P-450.
Biochem Soc Trans
; 25(4): S579, 1997 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-9450007
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