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1.
Nalfurafine promotes myelination in vitro and facilitates recovery from cuprizone + rapamycin-induced demyelination in mice.
Glia
; 2024 Jun 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38899723
2.
Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy-N-phenethyl-5-phenylmorphans.
Molecules
; 29(9)2024 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38731416
3.
A MOR Antagonist with High Potency and Antagonist Efficacy among Diastereomeric C9-Alkyl-Substituted N-Phenethyl-5-(3-hydroxy)phenylmorphans.
Molecules
; 28(14)2023 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37513283
4.
Potent MOR Agonists from 2'-Hydroxy-5,9-dimethyl-N-phenethyl Substituted-6,7-benzomorphans and from C8-Hydroxy, Methylene and Methyl Derivatives of N-Phenethylnormetazocine.
Molecules
; 28(23)2023 Nov 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38067439
5.
The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors.
Molecules
; 28(12)2023 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-37375403
6.
Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans.
Molecules
; 28(12)2023 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37375350
7.
Rational inhibitor design for Pseudomonas aeruginosa salicylate adenylation enzyme PchD.
J Biol Inorg Chem
; 27(6): 541-551, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35513576
8.
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans.
Molecules
; 27(24)2022 Dec 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36557961
9.
A Journey through Diastereomeric Space: The Design, Synthesis, In Vitro and In Vivo Pharmacological Activity, and Molecular Modeling of Novel Potent Diastereomeric MOR Agonists and Antagonists.
Molecules
; 27(19)2022 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36234992
10.
Discriminative-Stimulus Effects of Synthetic Cathinones in Squirrel Monkeys.
Int J Neuropsychopharmacol
; 24(8): 656-665, 2021 08 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-33909067
11.
Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent.
J Biomed Sci
; 28(1): 62, 2021 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34503531
12.
Strategies for Developing κ Opioid Receptor Agonists for the Treatment of Pain with Fewer Side Effects.
J Pharmacol Exp Ther
; 375(2): 332-348, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32913006
13.
Discovery of Small-Molecule Inhibitors Targeting the E3 Ubiquitin Ligase Activity of the Herpes Simplex Virus 1 ICP0 Protein Using an In Vitro High-Throughput Screening Assay.
J Virol
; 93(13)2019 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30996104
14.
The kappa-opioid receptor agonist, nalfurafine, blocks acquisition of oxycodone self-administration and oxycodone's conditioned rewarding effects in male rats.
Behav Pharmacol
; 31(8): 792-797, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32804774
15.
Further exploration of the structure-activity relationship of imidazoquinolines; identification of potent C7-substituted imidazoquinolines.
Bioorg Med Chem Lett
; 30(2): 126788, 2020 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31784317
16.
The Intriguing Effects of Substituents in the N-Phenethyl Moiety of Norhydromorphone: A Bifunctional Opioid from a Set of "Tail Wags Dog" Experiments.
Molecules
; 25(11)2020 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32517185
17.
Stuffed Methyltransferase Catalyzes the Penultimate Step of Pyochelin Biosynthesis.
Biochemistry
; 58(6): 665-678, 2019 02 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30525512
18.
Impact of Pharmacological Manipulation of the κ-Opioid Receptor System on Self-grooming and Anhedonic-like Behaviors in Male Mice.
J Pharmacol Exp Ther
; 370(1): 1-8, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30975792
19.
Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine.
J Pharmacol Exp Ther
; 371(2): 487-499, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31492823
20.
Scalable Regioselective and Stereoselective Synthesis of Functionalized (E)-4-Iodobut-3-en-1-ols: Gram-Scale Total Synthesis of Fungal Decanolides and Derivatives.
J Org Chem
; 83(2): 980-992, 2018 01 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-29271194