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1.
Targeting Bfl-1 via acute CDK9 inhibition overcomes intrinsic BH3-mimetic resistance in lymphomas.
Blood
; 137(21): 2947-2957, 2021 05 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-33259592
2.
Response to radiotherapy in pancreatic ductal adenocarcinoma is enhanced by inhibition of myeloid-derived suppressor cells using STAT3 anti-sense oligonucleotide.
Cancer Immunol Immunother
; 70(4): 989-1000, 2021 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-33097963
3.
Quantitative evaluation of trastuzumab deruxtecan pharmacokinetics and pharmacodynamics in mouse models of varying degrees of HER2 expression.
CPT Pharmacometrics Syst Pharmacol
; 13(6): 994-1005, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38532525
4.
PARP inhibition is a modulator of anti-tumor immune response in BRCA-deficient tumors.
Oncoimmunology
; 11(1): 2083755, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35756843
5.
Frontiers in cancer immunotherapy-a symposium report.
Ann N Y Acad Sci
; 1489(1): 30-47, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33184911
6.
Resistance to Durvalumab and Durvalumab plus Tremelimumab Is Associated with Functional STK11 Mutations in Patients with Non-Small Cell Lung Cancer and Is Reversed by STAT3 Knockdown.
Cancer Discov
; 11(11): 2828-2845, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34230008
7.
Macrophage Activation Status Rather than Repolarization Is Associated with Enhanced Checkpoint Activity in Combination with PI3Kγ Inhibition.
Mol Cancer Ther
; 20(6): 1080-1091, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33785652
8.
STAT3 Antisense Oligonucleotide Remodels the Suppressive Tumor Microenvironment to Enhance Immune Activation in Combination with Anti-PD-L1.
Clin Cancer Res
; 26(23): 6335-6349, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32943458
9.
AZD4573 Is a Highly Selective CDK9 Inhibitor That Suppresses MCL-1 and Induces Apoptosis in Hematologic Cancer Cells.
Clin Cancer Res
; 26(4): 922-934, 2020 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31699827
10.
Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies.
J Med Chem
; 63(24): 15564-15590, 2020 12 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-33306391
11.
Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors.
Nat Commun
; 10(1): 5167, 2019 11 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-31727888
12.
23814, an Inhibitory Antibody of Ligand-Mediated Notch1 Activation, Modulates Angiogenesis and Inhibits Tumor Growth without Gastrointestinal Toxicity.
Mol Cancer Ther
; 14(8): 1858-67, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25995436
13.
Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation.
Stem Cell Reports
; 2(5): 633-47, 2014 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-24936451
14.
Epithelial-to-mesenchymal transition activates PERK-eIF2α and sensitizes cells to endoplasmic reticulum stress.
Cancer Discov
; 4(6): 702-15, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24705811
15.
Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate.
Cell Stem Cell
; 8(2): 149-63, 2011 Feb 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-21295272
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