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1.
Suitability of different reconstructed human skin models in the skin and liver Chip2 microphysiological model to investigate the kinetics and first-pass skin metabolism of the hair dye, 4-amino-2-hydroxytoluene.
J Appl Toxicol
; 44(3): 333-343, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-37699698
2.
Application of a skin and liver Chip2 microphysiological model to investigate the route-dependent toxicokinetics and toxicodynamics of consumer-relevant doses of genistein.
J Appl Toxicol
; 44(2): 287-300, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-37700462
3.
Use of in vitro metabolism and biokinetics assays to refine predicted in vivo and in vitro internal exposure to the cosmetic ingredient, phenoxyethanol, for use in risk assessment.
Regul Toxicol Pharmacol
; 131: 105132, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35217105
4.
Demonstration of the first-pass metabolism in the skin of the hair dye, 4-amino-2-hydroxytoluene, using the Chip2 skin-liver microphysiological model.
J Appl Toxicol
; 41(10): 1553-1567, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33594739
5.
Development of a microphysiological skin-liver-thyroid Chip3 model and its application to evaluate the effects on thyroid hormones of topically applied cosmetic ingredients under consumer-relevant conditions.
Front Pharmacol
; 14: 1076254, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36843954
6.
Pharmacological properties of TRPM3 isoforms are determined by the length of the pore loop.
Br J Pharmacol
; 179(14): 3560-3575, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32780479
7.
Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects.
Sci Rep
; 12(1): 14158, 2022 08 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35986043
8.
Characterization of application scenario-dependent pharmacokinetics and pharmacodynamic properties of permethrin and hyperforin in a dynamic skin and liver multi-organ-chip model.
Toxicology
; 448: 152637, 2021 01 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-33220337
9.
Ca2+-dependent regulation and binding of calmodulin to multiple sites of Transient Receptor Potential Melastatin 3 (TRPM3) ion channels.
Cell Calcium
; 73: 40-52, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29880196
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