Detalles de la búsqueda
1.
Targeting PAX8 sensitizes ovarian cancer cells to ferroptosis by inhibiting glutathione synthesis.
Apoptosis
; 2024 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38853202
2.
Effect of ADHI on hepatic stellate cell activation and liver fibrosis in mice.
Biochem Biophys Res Commun
; 651: 98-106, 2023 04 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36801615
3.
The POR rs10954732 polymorphism decreases susceptibility to hepatocellular carcinoma and hepsin as a prognostic biomarker correlated with immune infiltration based on proteomics.
J Transl Med
; 20(1): 88, 2022 02 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35164791
4.
Use of proteomics to identify mechanisms of hepatocellular carcinoma with the CYP2D6*10 polymorphism and identification of ANGPTL6 as a new diagnostic and prognostic biomarker.
J Transl Med
; 19(1): 359, 2021 08 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-34412629
5.
Variation in the expression of cytochrome P450-related miRNAs and transcriptional factors in human livers: Correlation with cytochrome P450 gene phenotypes.
Toxicol Appl Pharmacol
; 412: 115389, 2021 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33385404
6.
From Genotype to Phenotype: Content and Activities of Cytochromes P450 2A6 in Human Liver In Vitro and Predicted In Vivo.
J Pharmacol Exp Ther
; 372(3): 320-330, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31882454
7.
A novel mass spectrometry method for the absolute quantification of several cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase enzymes in the human liver.
Anal Bioanal Chem
; 412(8): 1729-1740, 2020 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-32030490
8.
High CYP2E1 activity aggravates hepatofibrosis by limiting macrophage polarization towards the M2 phenotype.
Mol Carcinog
; 58(8): 1481-1491, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31116889
9.
CYP3A4/5 Activity Probed with Testosterone and Midazolam: Correlation between Two Substrates at the Microsomal and Enzyme Levels.
Mol Pharm
; 16(1): 382-392, 2019 01 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30517006
10.
Inhibitory effect of chlormethiazole on the toxicokinetics of diethylnitrosamine in normal and hepatofibrotic rats.
Drug Chem Toxicol
; 42(6): 600-607, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-29648470
11.
Effect of P450 Oxidoreductase Polymorphisms on the Metabolic Activities of Ten Cytochrome P450s Varied by Polymorphic CYP Genotypes in Human Liver Microsomes.
Cell Physiol Biochem
; 47(4): 1604-1616, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29949783
12.
Higher Activity of Alcohol Dehydrogenase Is Correlated with Hepatic Fibrogenesis.
J Pharmacol Exp Ther
; 367(3): 473-482, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30228113
13.
Higher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by Diethylnitrosamine.
J Pharmacol Exp Ther
; 365(2): 398-407, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29467309
14.
From hepatofibrosis to hepatocarcinogenesis: Higher cytochrome P450 2E1 activity is a potential risk factor.
Mol Carcinog
; 57(10): 1371-1382, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29917271
15.
Content and Activities of UGT2B7 in Human Liver In Vitro and Predicted In Vivo: A Bottom-Up Approach.
Drug Metab Dispos
; 46(9): 1351-1359, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29929994
16.
Intraindividual Variation and Correlation of Cytochrome P450 Activities in Human Liver Microsomes.
Mol Pharm
; 15(11): 5312-5318, 2018 11 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30346185
17.
From Genotype to Phenotype: Cytochrome P450 2D6-Mediated Drug Clearance in Humans.
Mol Pharm
; 14(3): 649-657, 2017 03 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28211700
18.
Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes.
J Pharmacol Exp Ther
; 358(1): 83-93, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27189963
19.
Correlation of Cytochrome P450 Oxidoreductase Expression with the Expression of 10 Isoforms of Cytochrome P450 in Human Liver.
Drug Metab Dispos
; 44(8): 1193-200, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27271371
20.
LC-MS/MS Analysis and Pharmacokinetics of Sodium (±)-5-Bromo-2-(α-hydroxypentyl) Benzoate (BZP), an Innovative Potent Anti-Ischemic Stroke Agent in Rats.
Molecules
; 21(4): 501, 2016 Apr 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-27092484