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1.
A non-retinoid antagonist of retinol-binding protein 4 rescues phenotype in a model of Stargardt disease without inhibiting the visual cycle.
J Biol Chem
; 293(29): 11574-11588, 2018 07 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29871924
2.
Cyclophilin D disruption attenuates lipopolysaccharide-induced inflammatory response in primary mouse macrophages.
Biochem Cell Biol
; 93(3): 241-50, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-25728038
3.
Quercetin increases the efficacy of glioblastoma treatment compared to standard chemoradiotherapy by the suppression of PI-3-kinase-Akt pathway.
Nutr Cancer
; 65(7): 1059-66, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24032376
4.
Protective effect of the poly(ADP-ribose) polymerase inhibitor PJ34 on mitochondrial depolarization-mediated cell death in hepatocellular carcinoma cells involves attenuation of c-Jun N-terminal kinase-2 and protein kinase B/Akt activation.
Mol Cancer
; 11: 34, 2012 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-22583868
5.
Facilitation of mitochondrial outer and inner membrane permeabilization and cell death in oxidative stress by a novel Bcl-2 homology 3 domain protein.
J Biol Chem
; 285(3): 2140-51, 2010 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19901022
6.
Identification of Transthyretin Tetramer Kinetic Stabilizers That Are Capable of Inhibiting the Retinol-Dependent Retinol Binding Protein 4-Transthyretin Interaction: Potential Novel Therapeutics for Macular Degeneration, Transthyretin Amyloidosis, and Their Common Age-Related Comorbidities.
J Med Chem
; 64(13): 9010-9041, 2021 07 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34138572
7.
Dopamine-induced programmed cell death is associated with cytochrome c release and caspase-3 activation in snail salivary gland cells.
Biol Cell
; 101(2): 105-16, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18601650
8.
Novel neuroprotective strategies in ischemic retinal lesions.
Int J Mol Sci
; 11(2): 544-561, 2010 Feb 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-20386654
9.
Comparative pharmacokinetics and pharmacodynamics of the advanced Retinol-Binding Protein 4 antagonist in dog and cynomolgus monkey.
PLoS One
; 15(1): e0228291, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-31978148
10.
Discovery of Bispecific Antagonists of Retinol Binding Protein 4 That Stabilize Transthyretin Tetramers: Scaffolding Hopping, Optimization, and Preclinical Pharmacological Evaluation as a Potential Therapy for Two Common Age-Related Comorbidities.
J Med Chem
; 63(19): 11054-11084, 2020 10 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32878437
11.
Influence of PACAP on oxidative stress and tissue injury following small-bowel autotransplantation.
J Mol Neurosci
; 37(2): 168-76, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18651248
12.
Design, Synthesis, and Preclinical Efficacy of Novel Nonretinoid Antagonists of Retinol-Binding Protein 4 in the Mouse Model of Hepatic Steatosis.
J Med Chem
; 62(11): 5470-5500, 2019 06 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-31079449
13.
Effects of PACAP on survival and renal morphology in rats subjected to renal ischemia/reperfusion.
J Mol Neurosci
; 36(1-3): 89-96, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18478450
14.
Effects of PACAP on the circadian changes of signaling pathways in chicken pinealocytes.
J Mol Neurosci
; 36(1-3): 220-6, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18592414
15.
Hyperosmotic stress-induced apoptotic signaling pathways in chondrocytes.
Bone
; 40(6): 1536-43, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17392049
16.
Expression and protective role of heme oxygenase-1 in delayed myocardial preconditioning.
Ann N Y Acad Sci
; 1095: 251-61, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17404038
17.
Cardioprotective action of urocortin in early pre- and postconditioning.
Ann N Y Acad Sci
; 1095: 228-39, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17404036
18.
Effects of pituitary adenylate cyclase activating polypeptide (PACAP) on the PKA-Bad-14-3-3 signaling pathway in glutamate-induced retinal injury in neonatal rats.
Neurotox Res
; 12(2): 95-104, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17967733
19.
PARP inhibition protects mitochondria and reduces ROS production via PARP-1-ATF4-MKP-1-MAPK retrograde pathway.
Free Radic Biol Med
; 108: 770-784, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28457938
20.
PACAP inhibits oxidative stress-induced activation of MAP kinase-dependent apoptotic pathway in cultured cardiomyocytes.
Ann N Y Acad Sci
; 1070: 293-7, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16891268