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1.
Towards antigen-specific Tregs for type 1 diabetes: Construction and functional assessment of pancreatic endocrine marker, HPi2-based chimeric antigen receptor.
Cell Immunol
; 358: 104224, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33068914
2.
The Type 1 Diabetes-Resistance Locus Idd22 Controls Trafficking of Autoreactive CTLs into the Pancreatic Islets of NOD Mice.
J Immunol
; 199(12): 3991-4000, 2017 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29109122
3.
Self-Transducible Bimodal PDX1-FOXP3 Protein Lifts Insulin Secretion and Curbs Autoimmunity, Boosting Tregs in Type 1 Diabetic Mice.
Mol Ther
; 26(1): 184-198, 2018 01 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28988715
4.
New Insights into Immunotherapy Strategies for Treating Autoimmune Diabetes.
Int J Mol Sci
; 20(19)2019 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-31561568
5.
Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes.
J Immunol
; 196(4): 1495-506, 2016 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26773144
6.
Dynamic interdomain interactions contribute to the inhibition of matrix metalloproteinases by tissue inhibitors of metalloproteinases.
J Biol Chem
; 286(23): 21002-12, 2011 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-21518756
7.
Biochemical characterization of the cellular glycosylphosphatidylinositol-linked membrane type-6 matrix metalloproteinase.
J Biol Chem
; 285(21): 16076-86, 2010 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-20308072
8.
Internal cleavages of the autoinhibitory prodomain are required for membrane type 1 matrix metalloproteinase activation, although furin cleavage alone generates inactive proteinase.
J Biol Chem
; 285(36): 27726-36, 2010 Sep 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-20605791
9.
The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis.
J Biol Chem
; 285(46): 35740-9, 2010 Nov 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-20837484
10.
Isolation and characterization of selective and potent human Fab inhibitors directed to the active-site region of the two-component NS2B-NS3 proteinase of West Nile virus.
Biochem J
; 427(3): 369-76, 2010 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-20156198
11.
Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes.
Front Endocrinol (Lausanne)
; 12: 737276, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34858326
12.
Inflammatory proprotein convertase-matrix metalloproteinase proteolytic pathway in antigen-presenting cells as a step to autoimmune multiple sclerosis.
J Biol Chem
; 284(44): 30615-26, 2009 Oct 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-19726693
13.
Biochemical evidence of the interactions of membrane type-1 matrix metalloproteinase (MT1-MMP) with adenine nucleotide translocator (ANT): potential implications linking proteolysis with energy metabolism in cancer cells.
Biochem J
; 420(1): 37-47, 2009 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-19232058
14.
Overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in endothelial cells accelerates coronary artery disease in a mouse model of familial hypercholesterolemia.
PLoS One
; 12(10): e0186426, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-29023576
15.
Transgenic Overexpression of Tissue-Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification.
J Am Heart Assoc
; 4(12)2015 Dec 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-26675253
16.
Autoimmune diabetes is suppressed by treatment with recombinant human tissue Kallikrein-1.
PLoS One
; 9(9): e107213, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25259810
17.
Preclinical characterization of recombinant human tissue kallikrein-1 as a novel treatment for type 2 diabetes mellitus.
PLoS One
; 9(8): e103981, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25100328
18.
Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development.
Diabetes
; 63(10): 3470-82, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24848066
19.
Alteration of Immune-Mechanisms by Human Microbiota and Development and Prevention of Human Diseases.
J Immunol Res
; 2017: 6985256, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-29445757
20.
Structure-based mutagenesis identifies important novel determinants of the NS2B cofactor of the West Nile virus two-component NS2B-NS3 proteinase.
J Gen Virol
; 89(Pt 3): 636-641, 2008 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-18272753