Detalles de la búsqueda
1.
The first-in-class pyrazole-based dual InhA-VEGFR inhibitors towards integrated antitubercular host-directed therapy.
Bioorg Chem
; 145: 107179, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38367430
2.
The hepatoprotective effect of 4-phenyltetrahydroquinolines on carbon tetrachloride induced hepatotoxicity in rats through autophagy inhibition.
Biol Res
; 57(1): 32, 2024 May 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-38797855
3.
Experimental investigation and molecular simulations of quinone related compounds as COX/LOX inhibitors.
Inflammopharmacology
; 2024 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-38858336
4.
Structure-guided approach on the role of substitution on amide-linked bipyrazoles and its effect on their anti-inflammatory activity.
J Enzyme Inhib Med Chem
; 37(1): 2179-2190, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35950562
5.
New pyrazolylpyrazoline derivatives as dual acting antimalarial-antileishamanial agents: synthesis, biological evaluation and molecular modelling simulations.
J Enzyme Inhib Med Chem
; 37(1): 2320-2333, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36036155
6.
Transforming iodoquinol into broad spectrum anti-tumor leads: Repurposing to modulate redox homeostasis.
Bioorg Chem
; 113: 105035, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34091287
7.
Design, Synthesis, and Anticancer Screening for Repurposed Pyrazolo[3,4-d]pyrimidine Derivatives on Four Mammalian Cancer Cell Lines.
Molecules
; 26(10)2021 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-34065773
8.
Synthesis, biological evaluation and modeling of hybrids from tetrahydro-1H-pyrazolo[3,4-b]quinolines as dual cholinestrase and COX-2 inhibitors.
Bioorg Chem
; 100: 103895, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32413626
9.
Design, synthesis, biological evaluation and in silico studies of certain aryl sulfonyl hydrazones conjugated with 1,3-diaryl pyrazoles as potent metallo-ß-lactamase inhibitors.
Bioorg Chem
; 105: 104386, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33137556
10.
Chlorinated tacrine analogs: Design, synthesis and biological evaluation of their anti-cholinesterase activity as potential treatment for Alzheimer's disease.
Bioorg Chem
; 86: 557-568, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30782574
11.
Synthesis of some new amide-linked bipyrazoles and their evaluation as anti-inflammatory and analgesic agents.
J Enzyme Inhib Med Chem
; 31(6): 1079-94, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26482802
12.
Structure Modification Converts the Hepatotoxic Tacrine into Novel Hepatoprotective Analogs.
ACS Omega
; 9(2): 2491-2503, 2024 Jan 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38250371
13.
Fabrication and Characterization of Silver Nanoparticle-Doped Chitosan/Carboxymethyl Cellulose Nanocomposites for Optoelectronic and Biological Applications.
ACS Omega
; 9(20): 22112-22122, 2024 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-38799360
14.
Synthesis, characterization, and evaluation of polymeric surfactants derived from PET plastic waste as green corrosion inhibitor of steel surfaces in marine environment for heavy industry.
RSC Adv
; 13(45): 31969-31988, 2023 Oct 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-37915447
15.
The Role of Pyrazolo[3,4-d]pyrimidine-Based Kinase Inhibitors in The Attenuation of CCl4-Induced Liver Fibrosis in Rats.
Antioxidants (Basel)
; 12(3)2023 Mar 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36978885
16.
Molecular Mechanics Simulations and Experimental Investigation of the Effect of Tadalafil on Various Inflammatory Pain Mediators.
ACS Omega
; 7(48): 43747-43758, 2022 Dec 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36506154
17.
Targeting multiple conformations of SARS-CoV2 Papain-Like Protease for drug repositioning: An in-silico study.
Comput Biol Med
; 131: 104295, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33662683
18.
Halting colorectal cancer metastasis via novel dual nanomolar MMP-9/MAO-A quinoxaline-based inhibitors; design, synthesis, and evaluation.
Eur J Med Chem
; 222: 113558, 2021 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34116327
19.
Investigation of chronic efficacy and safety profile of two potential anti-inflammatory bipyrazole-based compounds in experimental animals.
J Inflamm Res
; 11: 143-153, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29662323
20.
Synthesis of new pyrazolo[3,4-d]pyrimidine derivatives and evaluation of their anti-inflammatory and anticancer activities.
Chem Biol Drug Des
; 90(1): 83-96, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28032452