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1.
Characterization of Bile Acid Sulfate Conjugates as Substrates of Human Organic Anion Transporting Polypeptides.
Mol Pharm
; 20(6): 3020-3032, 2023 06 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37134201
2.
Natural Product Bis-Intercalator Depsipeptides as a New Class of Payloads for Antibody-Drug Conjugates.
Bioconjug Chem
; 30(1): 200-209, 2019 01 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-30543418
3.
Quantitative Conjugated Payload Measurement Using Enzymatic Release of Antibody-Drug Conjugate with Cleavable Linker.
Bioconjug Chem
; 28(2): 620-626, 2017 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28140559
4.
Where Did the Linker-Payload Go? A Quantitative Investigation on the Destination of the Released Linker-Payload from an Antibody-Drug Conjugate with a Maleimide Linker in Plasma.
Anal Chem
; 88(9): 4979-86, 2016 05 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27075639
5.
Natural Product Splicing Inhibitors: A New Class of Antibody-Drug Conjugate (ADC) Payloads.
Bioconjug Chem
; 27(8): 1880-8, 2016 08 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-27412791
6.
Preclinical Development of an anti-5T4 Antibody-Drug Conjugate: Pharmacokinetics in Mice, Rats, and NHP and Tumor/Tissue Distribution in Mice.
Bioconjug Chem
; 26(11): 2223-32, 2015 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-26180901
7.
A novel hydrophilic interaction chromatography assay characterization of 4-pyridoxic acid, an emergent renal organic anion transporter 1/3 transporter biomarker.
Bioanalysis
; 13(18): 1391-1400, 2021 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-34551579
8.
Identification of Glycochenodeoxycholate 3-O-Glucuronide and Glycodeoxycholate 3-O-Glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers.
Clin Pharmacol Ther
; 109(3): 646-657, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32961594
9.
Dose-Dependent Inhibition of OATP1B by Rifampicin in Healthy Volunteers: Comprehensive Evaluation of Candidate Biomarkers and OATP1B Probe Drugs.
Clin Pharmacol Ther
; 107(4): 1004-1013, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31628668
10.
Effect of chitosan glutamate, carbomer 974P, and EDTA on the in vitro Caco-2 permeability and oral pharmacokinetic profile of acyclovir in rats.
Drug Dev Ind Pharm
; 35(9): 1082-91, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19294548
11.
A multiplex HRMS assay for quantifying selected human plasma bile acids as candidate OATP biomarkers.
Bioanalysis
; 10(9): 645-657, 2018 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29749252
12.
Site Selection: a Case Study in the Identification of Optimal Cysteine Engineered Antibody Drug Conjugates.
AAPS J
; 19(4): 1123-1135, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28439809
13.
2017 White Paper: rise of hybrid LBA/LCMS immunogenicity assays (Part 2: hybrid LBA/LCMS biotherapeutics, biomarkers & immunogenicity assays and regulatory agencies' inputs).
Bioanalysis
; 9(23): 1895-1912, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29205053
14.
2017 White Paper on recent issues in bioanalysis: aren't BMV guidance/guidelines 'Scientific'? (Part 1 - LCMS: small molecules, peptides and small molecule biomarkers).
Bioanalysis
; 9(22): 1807-1825, 2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-29148835
15.
Quantification of fumarate and investigation of endogenous and exogenous fumarate stability in rat plasma by LC-MS/MS.
Bioanalysis
; 8(7): 661-75, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26978279
16.
Calculated conjugated payload from immunoassay and LC-MS intact protein analysis measurements of antibody-drug conjugate.
Bioanalysis
; 8(21): 2205-2217, 2016 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-27682846
17.
Biodistribution and Targeting of Anti-5T4 Antibody-Drug Conjugate Using Fluorescence Molecular Tomography.
Mol Cancer Ther
; 15(10): 2530-2540, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27466353
18.
Optimization of Tubulysin Antibody-Drug Conjugates: A Case Study in Addressing ADC Metabolism.
ACS Med Chem Lett
; 7(11): 977-982, 2016 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27882194
19.
In vivo biotransformations of antibody-drug conjugates.
Bioanalysis
; 7(13): 1649-64, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26226313
20.
Development of a high-throughput ultra performance liquid chromatography-mass spectrometry assay to profile 18 eicosanoids as exploratory biomarkers for atherosclerotic diseases.
J Chromatogr B Analyt Technol Biomed Life Sci
; 936: 25-32, 2013 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23973531