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1.
Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor.
Bioorg Med Chem Lett
; 27(11): 2634-2640, 2017 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28416131
2.
The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2'-α-chloro-2'-ß-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors.
Bioorg Med Chem Lett
; 27(18): 4323-4330, 2017 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28835346
3.
Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase.
Bioorg Med Chem Lett
; 26(18): 4536-4541, 2016 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27520942
4.
Synthesis and Antiviral Evaluation of Carbocyclic Nucleoside Analogs of Nucleoside Reverse Transcriptase Translocation Inhibitor MK-8591 (4'-Ethynyl-2-fluoro-2'-deoxyadenosine).
J Med Chem
; 61(20): 9218-9228, 2018 10 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-30265808
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