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1.
Computational analysis and in vitro evaluation of TMF 104, for its antioxidant, antimicrobial, and anticancer efficacies.
Biotechnol Appl Biochem
; 70(1): 148-156, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-35324037
2.
Computational and in vitro characterization of ICY-5: A potential candidate promoting mitochondrial apoptosis via the c-MET and STAT3 pathways.
J Cell Physiol
; 236(1): 146-156, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32484605
3.
High-throughput virtual screening and preclinical analysis identifies CB-1, a novel potent dual B-Raf/c-Raf inhibitor, effective against wild and mutant variants of B-Raf expression in colorectal carcinoma.
J Comput Aided Mol Des
; 35(12): 1165-1176, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34727304
4.
Thymoquinone inhibits IL-7-induced tumor progression and metastatic invasion in prostate cancer cells by attenuating matrix metalloproteinase activity and Akt/NF-κB signaling.
Biotechnol Appl Biochem
; 68(6): 1403-1411, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33128273
5.
FCX-146, a potent allosteric inhibitor of Akt kinase in cancer cells: Lead optimization of the second-generation arylidene indanone scaffold.
Biotechnol Appl Biochem
; 68(1): 82-91, 2021 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-32067263
6.
Structure activity evaluation and computational analysis identify potent, novel 3-benzylidene chroman-4-one analogs with anti-fungal, anti-oxidant, and anti-cancer activities.
Drug Dev Ind Pharm
; 47(9): 1459-1468, 2021 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-34726982
7.
MSCs ameliorates DPN induced cellular pathology via [Ca2+ ]i homeostasis and scavenging the pro-inflammatory cytokines.
J Cell Physiol
; 233(2): 1330-1341, 2018 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-28500758
8.
Feasibility of cord blood bank in high altitude Abha: preclinical impacts.
Cell Tissue Bank
; 19(3): 413-422, 2018 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-29460118
9.
Identification of second generation benzylidene chromanone analogues as novel, potent DHODH inhibitors in acute myeloid leukemia cells.
J Biomol Struct Dyn
; 41(13): 6168-6177, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-35869648
10.
High-throughput computational screening and in vitro evaluation identifies 5-(4-oxo-4H-3,1-benzoxazin-2-yl)-2-[3-(4-oxo-4H-3,1-benzoxazin-2-yl) phenyl]-1H-isoindole-1,3(2H)-dione (C3), as a novel EGFR-HER2 dual inhibitor in gastric tumors.
Oncol Res
; 32(2): 251-259, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38186572
11.
Insilco and Invitro approaches identify novel dual PI3K/AKT pathway inhibitors to control acute myeloid leukemia cell proliferations.
Med Oncol
; 39(12): 249, 2022 Oct 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36209300
12.
CB-RAF600E-1 exerts efficacy in vemurafenib-resistant and non-resistant-melanoma cells via dual inhibition of RAS/RAF/MEK/ERK and PI3K/Akt signaling pathways.
Saudi J Biol Sci
; 29(6): 103285, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35592740
13.
GC/MS characterization and computational kinome-wide screening of pomegranate fruit extract identifies key phytochemicals interacting to CDK kinases implicated in acute myeloid leukemia cells.
J Food Biochem
; 46(8): e14178, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35451509
14.
FNF-12, a novel benzylidene-chromanone derivative, attenuates inflammatory response in in vitro and in vivo asthma models mediated by M2-related Th2 cytokines via MAPK and NF-kB signaling.
Pharmacol Rep
; 74(1): 96-110, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-34468975
15.
A Combined Chemical, Computational, and In Vitro Approach Identifies SBL-105 as Novel DHODH Inhibitor in Acute Myeloid Leukemia Cells.
Oncol Res
; 28(9): 899-911, 2022 Jan 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-34353411
16.
Glucose and oleic acid mediate cellular alterations in GLP-1-induced insulin-positive differentiating UCBMSCs.
J Food Biochem
; 46(5): e14087, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35246864
17.
BV6 enhances apoptosis in Lung cancer cells by ameliorating caspase expressions through attenuation of XIAP, cIAP-1, and cIAP-2 proteins.
J Cancer Res Ther
; 18(6): 1651-1657, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36412426
18.
Computational docking and in vitro analysis identifies novel arylidene analogue FPMXY-14 against renal cancer cells by attenuating Akt.
Oncol Res
; 29(3): 217-227, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-37304673
19.
The SMAC mimetic AT-101 exhibits anti-tumor and anti-metastasis activity in lung adenocarcinoma cells by the IAPs/ caspase-dependent apoptosis and p65-NFÆB cross-talk.
Iran J Basic Med Sci
; 24(7): 969-977, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-34712428
20.
Cassia auriculata leaf extract ameliorates diabetic nephropathy by attenuating autophagic necroptosis via RIP-1/RIP-3-p-p38MAPK signaling.
J Food Biochem
; 45(7): e13810, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34080203