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1.
Regulation of ATP13A2 via PHD2-HIF1α Signaling Is Critical for Cellular Iron Homeostasis: Implications for Parkinson's Disease.
J Neurosci
; 36(4): 1086-95, 2016 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-26818499
2.
Sembragiline: A Novel, Selective Monoamine Oxidase Type B Inhibitor for the Treatment of Alzheimer's Disease.
J Pharmacol Exp Ther
; 362(3): 413-423, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28642233
3.
Mitochondrial Quality Control via the PGC1α-TFEB Signaling Pathway Is Compromised by Parkin Q311X Mutation But Independently Restored by Rapamycin.
J Neurosci
; 35(37): 12833-44, 2015 Sep 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-26377470
4.
Detrimental effects of oxidative losses in parkin activity in a model of sporadic Parkinson's disease are attenuated by restoration of PGC1alpha.
Neurobiol Dis
; 93: 115-20, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27185595
5.
The high-affinity D2/D3 agonist D512 protects PC12 cells from 6-OHDA-induced apoptotic cell death and rescues dopaminergic neurons in the MPTP mouse model of Parkinson's disease.
J Neurochem
; 131(1): 74-85, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24848702
6.
Intrinsic bioenergetic properties and stress sensitivity of dopaminergic synaptosomes.
J Neurosci
; 31(12): 4524-34, 2011 Mar 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-21430153
7.
Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease.
J Biol Chem
; 284(42): 29065-76, 2009 Oct 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-19679656
8.
Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease.
Neuron
; 37(6): 899-909, 2003 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-12670420
9.
Inducible alterations of glutathione levels in adult dopaminergic midbrain neurons result in nigrostriatal degeneration.
J Neurosci
; 27(51): 13997-4006, 2007 Dec 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-18094238
10.
Hsp90 Co-chaperone p23 contributes to dopaminergic mitochondrial stress via stabilization of PHD2: Implications for Parkinson's disease.
Neurotoxicology
; 65: 166-173, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29471019
11.
Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson's Disease.
Cell Rep
; 22(4): 930-940, 2018 01 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-29386135
12.
Chronic ferritin expression within murine dopaminergic midbrain neurons results in a progressive age-related neurodegeneration.
Brain Res
; 1140: 188-94, 2007 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-16631136
13.
A novel iron (II) preferring dopamine agonist chelator D-607 significantly suppresses α-syn- and MPTP-induced toxicities in vivo.
Neuropharmacology
; 123: 88-99, 2017 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28533164
14.
In vitro and in vivo neuroprotection by gamma-glutamylcysteine ethyl ester against MPTP: relevance to the role of glutathione in Parkinson's disease.
Neurosci Lett
; 402(1-2): 137-41, 2006 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-16644116
15.
Glutathione, iron and Parkinson's disease.
Biochem Pharmacol
; 64(5-6): 1037-48, 2002 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12213603
16.
Pharmacological prolyl hydroxylase domain inhibition as a therapeutic target for Parkinson's disease.
CNS Neurol Disord Drug Targets
; 13(1): 120-5, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24040809
17.
Lithium prevents parkinsonian behavioral and striatal phenotypes in an aged parkin mutant transgenic mouse model.
Brain Res
; 1591: 111-7, 2014 Dec 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-25452026
18.
A possible novel anti-inflammatory mechanism for the pharmacological prolyl hydroxylase inhibitor 3,4-dihydroxybenzoate: implications for use as a therapeutic for Parkinson's disease.
Parkinsons Dis
; 2012: 364684, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22666629
19.
Chronic expression of H-ferritin in dopaminergic midbrain neurons results in an age-related expansion of the labile iron pool and subsequent neurodegeneration: implications for Parkinson's disease.
Brain Res
; 1297: 17-22, 2009 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-19699718
20.
A disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial and cellular iron dysregulation in mammalian glutathione-depleted dopaminergic cells: implications for Parkinson's disease.
Antioxid Redox Signal
; 11(9): 2083-94, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19290777