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1.
Tumor Regression upon Intratumoral and Subcutaneous Dosing of the STING Agonist ALG-031048 in Mouse Efficacy Models.
Int J Mol Sci
; 24(22)2023 Nov 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38003463
2.
Distinct Effects of T-705 (Favipiravir) and Ribavirin on Influenza Virus Replication and Viral RNA Synthesis.
Antimicrob Agents Chemother
; 60(11): 6679-6691, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27572398
3.
Biochemical Evaluation of the Inhibition Properties of Favipiravir and 2'-C-Methyl-Cytidine Triphosphates against Human and Mouse Norovirus RNA Polymerases.
Antimicrob Agents Chemother
; 59(12): 7504-16, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26392512
4.
New Oligonucleotide 2'-O-Alkyl N3'âP5' (Thio)-Phosphoramidates as Potent Antisense Agents: Physicochemical Properties and Biological Activity.
Nucleic Acid Ther
; 33(5): 319-328, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37638793
5.
Synthesis and Anti-HCV Activity of Sugar-Modified Guanosine Analogues: Discovery of AL-611 as an HCV NS5B Polymerase Inhibitor for the Treatment of Chronic Hepatitis C.
J Med Chem
; 63(18): 10380-10395, 2020 09 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-32816483
6.
Synthesis and antiviral evaluation of 6-(alkyl-heteroaryl)furo[2,3-d]pyrimidin-2(3H)-one nucleosides and analogues with ethynyl, ethenyl, and ethyl spacers at C6 of the furopyrimidine core.
J Med Chem
; 50(16): 3897-905, 2007 Aug 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-17622128
7.
Structure-activity relationship analysis of mitochondrial toxicity caused by antiviral ribonucleoside analogs.
Antiviral Res
; 143: 151-161, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28412183
8.
Synthesis and biological evaluation of 6-(alkyn-1-yl)furo[2,3-d]pyrimidin-2(3H)-one base and nucleoside derivatives.
J Med Chem
; 49(1): 391-8, 2006 Jan 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-16392824
9.
Synthesis and Anti-Influenza Activity of Pyridine, Pyridazine, and Pyrimidine C-Nucleosides as Favipiravir (T-705) Analogues.
J Med Chem
; 59(10): 4611-24, 2016 05 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-27120583
10.
Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.
J Med Chem
; 48(7): 2695-700, 2005 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-15801860
11.
Synthesis of 5'-triphosphate mimics (P3Ms) of 3'-azido-3',5'-dideoxythymidine and 3',5'-dideoxy-5'-difluoromethylenethymidine as HIV-1 reverse transcriptase inhibitors.
Nucleosides Nucleotides Nucleic Acids
; 24(3): 179-89, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-15892257
12.
Synthesis of AZT 5'-triphosphate mimics and their inhibitory effects on HIV-1 reverse transcriptase.
J Med Chem
; 47(27): 6902-13, 2004 Dec 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-15615539
13.
The ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase.
PLoS One
; 8(7): e68347, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23874596
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