Detalles de la búsqueda
1.
Regulation of ATP13A2 via PHD2-HIF1α Signaling Is Critical for Cellular Iron Homeostasis: Implications for Parkinson's Disease.
J Neurosci
; 36(4): 1086-95, 2016 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-26818499
2.
Sembragiline: A Novel, Selective Monoamine Oxidase Type B Inhibitor for the Treatment of Alzheimer's Disease.
J Pharmacol Exp Ther
; 362(3): 413-423, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28642233
3.
Anti-Inflammatory and Neuroprotective Role of Natural Product Securinine in Activated Glial Cells: Implications for Parkinson's Disease.
Mediators Inflamm
; 2017: 8302636, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28473732
4.
Mitochondrial Quality Control via the PGC1α-TFEB Signaling Pathway Is Compromised by Parkin Q311X Mutation But Independently Restored by Rapamycin.
J Neurosci
; 35(37): 12833-44, 2015 Sep 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-26377470
5.
Detrimental effects of oxidative losses in parkin activity in a model of sporadic Parkinson's disease are attenuated by restoration of PGC1alpha.
Neurobiol Dis
; 93: 115-20, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27185595
6.
Single-cell transcriptomics reveals colonic immune perturbations during amyloid-ß driven Alzheimer's disease in mice.
bioRxiv
; 2024 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38352325
7.
Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer's disease.
Geroscience
; 45(2): 1095-1113, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36576642
8.
Potassium-chelating drug sodium polystyrene sulfonate enhances lysosomal function and suppresses proteotoxicity.
Geroscience
; 45(2): 1237-1245, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36018536
9.
A drug-like molecule engages nuclear hormone receptor DAF-12/FXR to regulate mitophagy and extend lifespan.
Nat Aging
; 3(12): 1529-1543, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37957360
10.
Taurine deficiency as a driver of aging.
Science
; 380(6649): eabn9257, 2023 06 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37289866
11.
Ability to delay neuropathological events associated with astrocytic MAO-B increase in a Parkinsonian mouse model: implications for early intervention on disease progression.
Neurobiol Dis
; 43(2): 527-32, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21809503
12.
Lithium protects against oxidative stress-mediated cell death in α-synuclein-overexpressing in vitro and in vivo models of Parkinson's disease.
J Neurosci Res
; 89(10): 1666-75, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21710541
13.
Trimethylamine modulates dauer formation, neurodegeneration, and lifespan through tyra-3/daf-11 signaling in Caenorhabditis elegans.
Aging Cell
; 20(5): e13351, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33819374
14.
Ability to delay neuropathological events associated with astrocytic MAO-B increase in a Parkinsonian mouse model: implications for early intervention on disease progression.
Neurobiol Dis
; 40(2): 444-8, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20655384
15.
Microdose lithium reduces cellular senescence in human astrocytes - a potential pharmacotherapy for COVID-19?
Aging (Albany NY)
; 12(11): 10035-10040, 2020 06 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-32534451
16.
Gedunin Inhibits Oligomeric Aß1-42-Induced Microglia Activation Via Modulation of Nrf2-NF-κB Signaling.
Mol Neurobiol
; 56(11): 7851-7862, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-31127528
17.
Inducible alterations of glutathione levels in adult dopaminergic midbrain neurons result in nigrostriatal degeneration.
J Neurosci
; 27(51): 13997-4006, 2007 Dec 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-18094238
18.
Hsp90 Co-chaperone p23 contributes to dopaminergic mitochondrial stress via stabilization of PHD2: Implications for Parkinson's disease.
Neurotoxicology
; 65: 166-173, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29471019
19.
Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson's Disease.
Cell Rep
; 22(4): 930-940, 2018 01 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-29386135
20.
Cellular senescence and the aging brain.
Exp Gerontol
; 68: 3-7, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25281806