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1.
In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease.
Proc Natl Acad Sci U S A
; 116(20): 10156-10161, 2019 05 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-31028142
2.
BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells.
J Pharmacol Exp Ther
; 357(3): 554-61, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27048659
3.
Rodent selectivity of piperidine-4-yl-1H-indoles, a series of CC chemokine receptor-3 (CCR3) antagonists: insights from a receptor model.
Bioorg Med Chem Lett
; 25(2): 229-35, 2015 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25497216
4.
Virtual clinical QT exposure-response studies - A translational computational approach.
J Pharmacol Toxicol Methods
; 126: 107498, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38432528
5.
Optimization of bioanalysis of dried blood samples.
J Pharmacol Toxicol Methods
; 123: 107296, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37482323
6.
Discovery of BI 7446: A Potent Cyclic Dinucleotide STING Agonist with Broad-Spectrum Variant Activity for the Treatment of Cancer.
J Med Chem
; 66(14): 9376-9400, 2023 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37450324
7.
Ion Channel Expression and Electrophysiology of Singular Human (Primary and Induced Pluripotent Stem Cell-Derived) Cardiomyocytes.
Cells
; 10(12)2021 11 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-34943878
8.
Behavioral deficits and subregion-specific suppression of LTP in mice expressing a population of mutant NMDA receptors throughout the hippocampus.
Learn Mem
; 16(10): 635-44, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19794189
9.
Characterization of iCell cardiomyocytes using single-cell RNA-sequencing methods.
J Pharmacol Toxicol Methods
; 106: 106915, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32871229
10.
Comparison of in vitro and computational experiments on the relation of inter-beat interval and duration of repolarization in a specific type of human induced pluripotent stem cell-derived cardiomyocytes.
PLoS One
; 14(9): e0221763, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31498812
11.
Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice.
PLoS One
; 13(1): e0191225, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29385160
12.
Influence of field potential duration on spontaneous beating rate of human induced pluripotent stem cell-derived cardiomyocytes: Implications for data analysis and test system selection.
J Pharmacol Toxicol Methods
; 82: 74-82, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27521052
13.
Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling.
J Neurosci
; 23(6): 2323-32, 2003 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12657691
14.
An integrated platform for simultaneous multi-well field potential recording and Fura-2-based calcium transient ratiometry in human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes.
J Pharmacol Toxicol Methods
; 75: 91-100, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25921432
15.
Solubility assessment and on-line exposure confirmation in a patch-clamp assay for hERG (human ether-a-go-go-related gene) potassium channel inhibition.
J Pharmacol Toxicol Methods
; 70(2): 182-7, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25117629
16.
Restoring long-term potentiation impaired by amyloid-beta oligomers: comparison of an acetylcholinesterase inhibitior and selective neuronal nicotinic receptor agonists.
Brain Res Bull
; 96: 28-38, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23639920
17.
Inhibition of acetylcholinesterase and phosphodiesterase-9A has differential effects on hippocampal early and late LTP.
Neuropharmacology
; 62(5-6): 1964-74, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22245562
18.
Differential effect of the mGlu5 receptor positive allosteric modulator ADX-47273 on early and late hippocampal LTP.
Neuropharmacology
; 61(4): 707-14, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21640734
19.
A multi-slice recording system for stable late phase hippocampal long-term potentiation experiments.
J Neurosci Methods
; 194(2): 394-401, 2011 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21087635
20.
Differential effects of subtype-specific nicotinic acetylcholine receptor agonists on early and late hippocampal LTP.
Eur J Pharmacol
; 671(1-3): 26-32, 2011 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-21968142