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1.
Determination of Endogenous Concentrations of Uracil and Dihydrouracil in Dried Saliva Spots by LC-MS/MS: Method Development, Validation, and Clinical Application.
Ther Drug Monit
; 41(3): 383-390, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30807536
2.
Influence of CYP2D6 and CYP3A4 Phenotypes, Drug Interactions, and Vitamin D Status on Tamoxifen Biotransformation.
Ther Drug Monit
; 37(6): 733-44, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25853922
3.
DPD functional tests in plasma, fresh saliva and dried saliva samples as predictors of 5-fluorouracil exposure and occurrence of drug-related severe toxicity.
Clin Biochem
; 56: 18-25, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29625079
4.
Analytical and clinical validation of a dried blood spot assay for the determination of paclitaxel using high-performance liquid chromatography-tandem mass spectrometry.
Clin Biochem
; 54: 123-130, 2018 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-29514052
5.
Pharmacogenetic and Pharmacokinetic Dose Individualization of the Taxane Chemotherapeutic Drugs Paclitaxel and Docetaxel.
Curr Med Chem
; 24(33): 3559-3582, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28641556
6.
Endogenous plasma and salivary uracil to dihydrouracil ratios and DPYD genotyping as predictors of severe fluoropyrimidine toxicity in patients with gastrointestinal malignancies.
Clin Biochem
; 49(16-17): 1221-1226, 2016 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-27399164
7.
DBS sampling in imatinib therapeutic drug monitoring: from method development to clinical application.
Bioanalysis
; 7(16): 2105-17, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26327189
8.
CYP3A4*22 is related to increased plasma levels of 4-hydroxytamoxifen and partially compensates for reduced CYP2D6 activation of tamoxifen.
Pharmacogenomics
; 16(6): 601-17, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25893704
9.
Ultra-high performance liquid chromatography tandem mass spectrometric method for the determination of tamoxifen, N-desmethyltamoxifen, 4-hydroxytamoxifen and endoxifen in dried blood spots--development, validation and clinical application during breast cancer adjuvant therapy.
Talanta
; 132: 775-84, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25476377
10.
Development, validation and clinical application of a HPLC-FL method for CYP2D6 phenotyping in South Brazilian breast cancer patients.
Clin Biochem
; 47(12): 1084-90, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24747158
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