Detalles de la búsqueda
1.
Comparison of Rat Hepatocyte 2D-Monocultures and Hepatocytes Non-Parenchymal Cell Co-Cultures for Assessing Chemical Toxicity.
Int J Toxicol
; 42(1): 19-36, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36523256
2.
Key Challenges and Recommendations for In Vitro Testing of Tobacco Products for Regulatory Applications: Consideration of Test Materials and Exposure Parameters.
Altern Lab Anim
; 51(1): 55-79, 2023 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-36821083
3.
The common indoor air pollutant α-pinene is metabolised to a genotoxic metabolite α-pinene oxide.
Xenobiotica
; 52(3): 301-311, 2022 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-35473450
4.
Sensitive CometChip assay for screening potentially carcinogenic DNA adducts by trapping DNA repair intermediates.
Nucleic Acids Res
; 48(3): e13, 2020 02 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-31822921
5.
Identification of compound causing yellow bone discoloration following alpha-glycosyl isoquercitrin exposure in Sprague-Dawley rats.
Arch Toxicol
; 94(7): 2413-2421, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32388820
6.
Integrated in silico and in vitro genotoxicity assessment of thirteen data-poor substances.
Regul Toxicol Pharmacol
; 107: 104427, 2019 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-31336127
7.
Transcriptional profiling of male CD-1 mouse lungs and Harderian glands supports the involvement of calcium signaling in acrylamide-induced tumors.
Regul Toxicol Pharmacol
; 95: 75-90, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29475067
8.
Impact of Acrylamide on Calcium Signaling and Cytoskeletal Filaments in Testes From F344 Rat.
Int J Toxicol
; 36(2): 124-132, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28403741
9.
Differential genotoxicity of acrylamide in the micronucleus and Pig-a gene mutation assays in F344 rats and B6C3F1 mice.
Mutagenesis
; 31(6): 617-626, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27338305
10.
Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water.
Crit Rev Toxicol
; 45(1): 1-43, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25605026
11.
Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furan.
Toxicol Appl Pharmacol
; 274(1): 63-77, 2014 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24183702
12.
Genotoxicity assessment in HepaRG™ cells as a new approach methodology follow up to a positive response in the human TK6 cell micronucleus assay: Naphthalene case study.
Environ Mol Mutagen
; 64(8-9): 458-465, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37704589
13.
Increasing confidence in new approach methodologies for inhalation risk assessment with multiple end point assays using 5-day repeated exposure to 1,3-dichloropropene.
Toxicology
; 499: 153642, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37863466
14.
Early microRNA responses in rodent liver mediated by furan exposure establish dose thresholds for later adverse outcomes.
Toxicol Lett
; 384: 105-114, 2023 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37517673
15.
Error-corrected duplex sequencing enables direct detection and quantification of mutations in human TK6 cells with strong inter-laboratory consistency.
Mutat Res Genet Toxicol Environ Mutagen
; 889: 503649, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-37491114
16.
Adopting Duplex Sequencing™ Technology for Genetic Toxicity Testing: A Proof-of-Concept Mutagenesis Experiment with N-Ethyl-N-Nitrosourea (ENU)-Exposed Rats.
bioRxiv
; 2023 May 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37214853
17.
Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats.
Mutat Res Genet Toxicol Environ Mutagen
; 891: 503669, 2023 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-37770135
18.
Improvement of in vivo genotoxicity assessment: combination of acute tests and integration into standard toxicity testing.
Mutat Res
; 723(2): 108-20, 2011 Aug 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-21182982
19.
Transcriptomic pathway and benchmark dose analysis of Bisphenol A, Bisphenol S, Bisphenol F, and 3,3',5,5'-Tetrabromobisphenol A in H9 human embryonic stem cells.
Toxicol In Vitro
; 72: 105097, 2021 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-33476716
20.
A Modern Genotoxicity Testing Paradigm: Integration of the High-Throughput CometChip® and the TGx-DDI Transcriptomic Biomarker in Human HepaRG™ Cell Cultures.
Front Public Health
; 9: 694834, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34485225