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1.
Autophagy modulators for the treatment of oral and esophageal squamous cell carcinomas.
Med Res Rev
; 40(3): 1002-1060, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31742748
2.
(+)-(R)- and (-)-(S)-Perhexiline maleate: Enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages.
Bioorg Chem
; 102: 104067, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32663671
3.
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II).
Bioorg Chem
; 89: 103020, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31185392
4.
Enantioselective Synthesis of Thailanstatin A Methyl Ester and Evaluation of in Vitro Splicing Inhibition.
J Org Chem
; 83(9): 5187-5198, 2018 05 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29696980
5.
Novel peptidomimetics as BACE-1 inhibitors: synthesis, molecular modeling, and biological studies.
Bioorg Med Chem Lett
; 23(1): 85-9, 2013 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23218605
6.
Design and Synthesis of Oligopeptidic Parvulin Inhibitors.
ChemMedChem
; 17(11): e202200050, 2022 06 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35357776
7.
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability.
Eur J Med Chem
; 238: 114409, 2022 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35551034
8.
Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy.
Eur J Med Chem
; 235: 114274, 2022 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35344902
9.
A non-toxic, reversibly released imaging probe for oral cancer that is derived from natural compounds.
Sci Rep
; 11(1): 14069, 2021 07 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34234213
10.
Synthesis and biological evaluation of benzhydryl-based antiplasmodial agents possessing Plasmodium falciparum chloroquine resistance transporter (PfCRT) inhibitory activity.
Eur J Med Chem
; 215: 113227, 2021 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33601312
11.
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation.
Eur J Med Chem
; 212: 112998, 2021 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33199154
12.
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents.
ACS Chem Neurosci
; 12(9): 1716-1736, 2021 05 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33890763
13.
Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors.
J Med Chem
; 64(14): 9960-9988, 2021 07 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34251197
14.
Retinitis Pigmentosa and Retinal Degenerations: Deciphering Pathways and Targets for Drug Discovery and Development.
ACS Chem Neurosci
; 11(15): 2173-2191, 2020 08 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32589402
15.
Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists.
J Med Chem
; 63(22): 13466-13513, 2020 11 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32845153
16.
Telomerase-based Cancer Therapeutics: A Review on their Clinical Trials.
Curr Top Med Chem
; 20(6): 433-457, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-31894749
17.
Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents.
ACS Infect Dis
; 6(1): 100-113, 2020 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31661956
18.
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation.
ACS Med Chem Lett
; 11(11): 2268-2276, 2020 Nov 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33214839
19.
A light in the dark: state of the art and perspectives in optogenetics and optopharmacology for restoring vision.
Future Med Chem
; 11(5): 463-487, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30907134
20.
Raising the bar in anticancer therapy: recent advances in, and perspectives on, telomerase inhibitors.
Drug Discov Today
; 24(7): 1370-1388, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31136800