Detalles de la búsqueda
1.
An allosteric inhibitor of sirtuin 2 blocks hepatitis B virus covalently closed circular DNA establishment and its transcriptional activity.
Antiviral Res
; 226: 105888, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38641024
2.
The structure of XIAP BIR2: understanding the selectivity of the BIR domains.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 9): 1717-25, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23999295
3.
Inhibition of SIRT2 promotes death of human cytomegalovirus-infected peripheral blood monocytes via apoptosis and necroptosis.
Antiviral Res
; 217: 105698, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37562606
4.
An allosteric inhibitor of sirtuin 2 deacetylase activity exhibits broad-spectrum antiviral activity.
J Clin Invest
; 133(12)2023 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37317966
5.
Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis.
Nat Cancer
; 3(1): 43-59, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35121987
6.
Selective growth inhibition of tumor cells by a novel histone deacetylase inhibitor, NVP-LAQ824.
Cancer Res
; 64(2): 689-95, 2004 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-14744786
7.
The discovery of NVP-LAQ824: from concept to clinic.
Curr Med Chem
; 10(22): 2393-402, 2003 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-14529481
8.
Recent advances in the discovery of small molecule histone deacetylase inhibitors.
Curr Opin Drug Discov Devel
; 5(4): 487-99, 2002 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12197307
9.
Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates.
J Med Chem
; 45(4): 753-7, 2002 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-11831887
10.
N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824).
J Med Chem
; 46(21): 4609-24, 2003 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-14521422
11.
Molecular and cellular basis for the anti-proliferative effects of the HDAC inhibitor LAQ824.
Novartis Found Symp
; 259: 249-66; discussion 266-8, 285-8, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15171259
12.
Use of a novel histone deacetylase inhibitor to induce apoptosis in cell lines of acute lymphoblastic leukemia.
Haematologica
; 89(4): 419-26, 2004 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15075075
13.
Highly Regioselective Nitration Reactions Provide a Versatile Method of Functionalizing Benzocycloheptapyridine Tricyclic Ring Systems: Application toward Preparation of Nanomolar Inhibitors of Farnesyl Protein Transferase.
J Org Chem
; 63(3): 445-451, 1998 Feb 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-11672031
14.
Optimization of benzodiazepinones as selective inhibitors of the X-linked inhibitor of apoptosis protein (XIAP) second baculovirus IAP repeat (BIR2) domain.
J Med Chem
; 56(20): 7788-803, 2013 Oct 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-24093940
15.
Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain.
J Med Chem
; 56(20): 7772-87, 2013 Oct 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-24083782
16.
Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors.
J Med Chem
; 54(13): 4752-72, 2011 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-21650221
17.
NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.
Blood
; 102(7): 2615-22, 2003 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12816865
18.
Psammaplins from the sponge Pseudoceratina purpurea: inhibition of both histone deacetylase and DNA methyltransferase.
J Org Chem
; 68(10): 3866-73, 2003 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-12737565
Resultados
1 -
18
de 18
1
Próxima >
>>