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1.
The discovery of NVP-LAQ824: from concept to clinic.
Curr Med Chem
; 10(22): 2393-402, 2003 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-14529481
2.
Recent advances in the discovery of small molecule histone deacetylase inhibitors.
Curr Opin Drug Discov Devel
; 5(4): 487-99, 2002 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12197307
3.
Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates.
J Med Chem
; 45(4): 753-7, 2002 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-11831887
4.
N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824).
J Med Chem
; 46(21): 4609-24, 2003 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-14521422
5.
Optimization of benzodiazepinones as selective inhibitors of the X-linked inhibitor of apoptosis protein (XIAP) second baculovirus IAP repeat (BIR2) domain.
J Med Chem
; 56(20): 7788-803, 2013 Oct 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-24093940
6.
Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain.
J Med Chem
; 56(20): 7772-87, 2013 Oct 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-24083782
7.
Psammaplins from the sponge Pseudoceratina purpurea: inhibition of both histone deacetylase and DNA methyltransferase.
J Org Chem
; 68(10): 3866-73, 2003 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-12737565
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