Detalles de la búsqueda
1.
Cardiotoxicity and ROS Protection Assessment of three Structure-Related N-Acylhydrazones with Potential for the Treatment of Neurodegenerative Diseases.
Chem Biodivers
; 21(3): e202400356, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38353670
2.
Effects of the aldehyde-derived ring substituent on the properties of two new bioinspired trimethoxybenzoylhydrazones: methyl vs nitro groups.
Beilstein J Org Chem
; 19: 1713-1727, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38025090
3.
Full Equilibrium Picture in Aqueous Binary and Ternary Systems Involving Copper(II), 1-Methylimidazole-Containing Hydrazonic Ligands, and the 103-112 Human Prion Protein Fragment.
Inorg Chem
; 61(1): 723-737, 2022 Jan 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34918515
4.
Targeted and Untargeted Metabolomic Analyses Reveal Organ Specificity of Specialized Metabolites in the Model Grass Brachypodium distachyon.
Molecules
; 27(18)2022 Sep 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36144695
5.
Novel luminescent benzopyranothiophene- and BODIPY-derived aroylhydrazonic ligands and their dicopper(II) complexes: syntheses, antiproliferative activity and cellular uptake studies.
J Biol Inorg Chem
; 26(6): 675-688, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34417682
6.
Isoxazole-Derived Aroylhydrazones and Their Dinuclear Copper(II) Complexes Show Antiproliferative Activity on Breast Cancer Cells with a Potentially Alternative Mechanism Of Action.
Chembiochem
; 21(17): 2474-2486, 2020 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32282111
7.
The aroylhydrazone INHHQ prevents memory impairment induced by Alzheimer's-linked amyloid-ß oligomers in mice.
Behav Pharmacol
; 31(8): 738-747, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32773452
8.
Impact of pyridine-2-carboxaldehyde-derived aroylhydrazones on the copper-catalyzed oxidation of the M112A PrP103-112 mutant fragment.
J Biol Inorg Chem
; 24(8): 1231-1244, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31401689
9.
Binucleating Hydrazonic Ligands and Their µ-Hydroxodicopper(II) Complexes as Promising Structural Motifs for Enhanced Antitumor Activity.
Inorg Chem
; 58(13): 8800-8819, 2019 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31247881
10.
Aroylhydrazones constitute a promising class of 'metal-protein attenuating compounds' for the treatment of Alzheimer's disease: a proof-of-concept based on the study of the interactions between zinc(II) and pyridine-2-carboxaldehyde isonicotinoyl hydrazone.
J Biol Inorg Chem
; 23(8): 1227-1241, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30145655
11.
Metal-based superoxide dismutase and catalase mimics reduce oxidative stress biomarkers and extend life span of Saccharomyces cerevisiae.
Biochem J
; 474(2): 301-315, 2017 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28062841
12.
Theoretical Proposal for the Whole Phosphate Diester Hydrolysis Mechanism Promoted by a Catalytic Promiscuous Dinuclear Copper(II) Complex.
Inorg Chem
; 55(6): 2806-18, 2016 Mar 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-26934384
13.
Secondary metabolites in plant innate immunity: conserved function of divergent chemicals.
New Phytol
; 206(3): 948-964, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25659829
14.
Repurposing CRISPR-Cas13 systems for robust mRNA trans-splicing.
Nat Commun
; 15(1): 2325, 2024 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38485709
15.
New mescaline-related N-acylhydrazone and its unsubstituted benzoyl derivative: Promising metallophores for copper-associated deleterious effects relief in Alzheimer's disease.
J Inorg Biochem
; 238: 112033, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36396525
16.
Copper(II) complexes of a furan-containing aroylhydrazonic ligand: syntheses, structural studies, solution chemistry and interaction with HSA.
Dalton Trans
; 52(47): 17731-17746, 2023 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37916692
17.
X1INH, an improved next-generation affinity-optimized hydrazonic ligand, attenuates abnormal copper(I)/copper(II)-α-Syn interactions and affects protein aggregation in a cellular model of synucleinopathy.
Dalton Trans
; 49(45): 16252-16267, 2020 Nov 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32391542
18.
Tridentate N-Acylhydrazones as Moderate Ligands for the Potential Management of Cognitive Decline Associated With Metal-Enhanced Neuroaggregopathies.
Front Neurol
; 13: 828654, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35250832
19.
A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies.
J Inorg Biochem
; 170: 160-168, 2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28249224
20.
Combining Human Computing and Machine Learning to Make Sense of Big (Aerial) Data for Disaster Response.
Big Data
; 4(1): 47-59, 2016 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27441584