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1.
Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function.
J Biol Chem
; 295(15): 5136-5151, 2020 04 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32132173
2.
CYP2C9 structure-metabolism relationships: substrates, inhibitors, and metabolites.
J Med Chem
; 50(22): 5382-91, 2007 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17915853
3.
CYP2C9 structure-metabolism relationships: optimizing the metabolic stability of COX-2 inhibitors.
J Med Chem
; 50(18): 4444-52, 2007 Sep 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-17696334
4.
The molecular and enzyme kinetic basis for the diminished activity of the cytochrome P450 2D6.17 (CYP2D6.17) variant. Potential implications for CYP2D6 phenotyping studies and the clinical use of CYP2D6 substrate drugs in some African populations.
Biochem Pharmacol
; 64(9): 1387-98, 2002 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12392820
5.
Combining pharmacophore and protein modeling to predict CYP450 inhibitors and substrates.
Methods Enzymol
; 357: 133-44, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-12424905
6.
Virtual screening and scaffold hopping based on GRID molecular interaction fields.
J Chem Inf Model
; 45(5): 1313-23, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-16180908
7.
Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate.
J Pharmacol Exp Ther
; 300(2): 399-407, 2002 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-11805197
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