Detalles de la búsqueda
1.
Hypoxia and Hypoxia-Inducible Factor-1α Regulate Endoplasmic Reticulum Stress in Nucleus Pulposus Cells: Implications of Endoplasmic Reticulum Stress for Extracellular Matrix Secretion.
Am J Pathol
; 191(3): 487-502, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33307037
2.
Understanding embryonic development for cell-based therapies of intervertebral disc degeneration: Toward an effort to treat disc degeneration subphenotypes.
Dev Dyn
; 250(3): 302-317, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32564440
3.
NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis.
Dev Biol
; 455(2): 369-381, 2019 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31301300
4.
COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells.
J Biol Chem
; 293(23): 8969-8981, 2018 06 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29700115
5.
TNF-α promotes nuclear enrichment of the transcription factor TonEBP/NFAT5 to selectively control inflammatory but not osmoregulatory responses in nucleus pulposus cells.
J Biol Chem
; 292(42): 17561-17575, 2017 10 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-28842479
6.
PHD3 is a transcriptional coactivator of HIF-1α in nucleus pulposus cells independent of the PKM2-JMJD5 axis.
FASEB J
; 31(9): 3831-3847, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28495754
7.
RNA Sequencing Reveals a Role of TonEBP Transcription Factor in Regulation of Pro-inflammatory Genes in Response to Hyperosmolarity in Healthy Nucleus Pulposus Cells: A HOMEOSTATIC RESPONSE?
J Biol Chem
; 291(52): 26686-26697, 2016 Dec 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-27875309
8.
Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.
J Biol Chem
; 290(11): 7195-207, 2015 Mar 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-25635047
9.
Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1ß in nucleus pulposus cells: novel regulation by AP-1, Sp1, and Sp3.
Am J Pathol
; 185(2): 485-95, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25476526
10.
FIH-1-Mint3 axis does not control HIF-1 transcriptional activity in nucleus pulposus cells.
J Biol Chem
; 289(30): 20594-605, 2014 Jul 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-24867948
11.
CCN2 suppresses catabolic effects of interleukin-1ß through α5ß1 and αVß3 integrins in nucleus pulposus cells: implications in intervertebral disc degeneration.
J Biol Chem
; 289(11): 7374-87, 2014 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-24464580
12.
Tumor necrosis factor-α- and interleukin-1ß-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: implications in inflammatory disc disease.
Am J Pathol
; 184(9): 2560-72, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25063530
13.
HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells.
FASEB J
; 28(6): 2455-65, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24558194
14.
Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity.
J Biol Chem
; 288(18): 12654-66, 2013 May 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-23530034
15.
Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration.
J Biol Chem
; 288(23): 16761-16774, 2013 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-23589286
16.
Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB.
Am J Pathol
; 182(6): 2310-21, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23602832
17.
Tumor necrosis factor α- and interleukin-1ß-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1.
Arthritis Rheum
; 65(3): 832-42, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23233369
18.
Proteoglycan Dysfunction: A Common Link Between Intervertebral Disc Degeneration and Skeletal Dysplasia.
Neurospine
; 21(1): 162-178, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38569642
19.
Sdc4 deletion perturbs intervertebral disc matrix homeostasis and promotes early osteopenia in the aging mouse spine.
Matrix Biol
; 2024 May 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-38806135
20.
Toward understanding the cellular control of vertebrate mineralization: The potential role of mitochondria.
Bone
; 185: 117112, 2024 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38697384