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1.
The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination.
Int J Mol Sci
; 23(15)2022 Jul 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-35955488
2.
Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies.
Angew Chem Int Ed Engl
; 60(11): 6029-6035, 2021 03 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33245574
3.
Combined analytical approaches to define biodistribution and biological activity of semi-synthetic berberrubine, the active metabolite of natural berberine.
Anal Bioanal Chem
; 410(15): 3533-3545, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29411090
4.
Effects of trans-stilbene and terphenyl compounds on different strains of Leishmania and on cytokines production from infected macrophages.
Exp Parasitol
; 184: 31-38, 2018 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-29154845
5.
Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A.
Org Biomol Chem
; 14(46): 10981-10987, 2016 11 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27827510
6.
In vitro antileishmanial activity of trans-stilbene and terphenyl compounds.
Exp Parasitol
; 166: 1-9, 2016 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-26953250
7.
Berberine and its metabolites: relationship between physicochemical properties and plasma levels after administration to human subjects.
J Nat Prod
; 77(4): 766-72, 2014 Apr 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-24593257
8.
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer.
Eur J Med Chem
; 265: 116114, 2024 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38194775
9.
TTAS a new stilbene derivative that induces apoptosis in Leishmania infantum.
Exp Parasitol
; 133(1): 37-43, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23103597
10.
Application of an "inhalation by design" approach to the identification and in-vitro evaluation of novel purine based PI3Kδ inhibitors.
Eur J Med Chem
; 254: 115331, 2023 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37094451
11.
Preomic profile of BxPC-3 cells after treatment with BRC4.
J Proteomics
; 288: 104983, 2023 09 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37536521
12.
Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5.
J Med Chem
; 66(14): 9797-9822, 2023 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37440686
13.
Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives.
J Med Chem
; 65(7): 5212-5243, 2022 04 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35377645
14.
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One.
J Med Chem
; 65(14): 9507-9530, 2022 07 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-35816671
15.
Identification of RAD51-BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry.
ACS Med Chem Lett
; 13(8): 1262-1269, 2022 Aug 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35978685
16.
Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment.
Biochim Biophys Acta Gen Subj
; 1865(1): 129760, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33035602
17.
Antiparasitic Effect of Stilbene and Terphenyl Compounds against Trypanosoma cruzi Parasites.
Pharmaceuticals (Basel)
; 14(11)2021 Nov 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34832980
18.
Free-Radical-Mediated Formation of Trans-Cardiolipin Isomers, Analytical Approaches for Lipidomics and Consequences of the Structural Organization of Membranes.
Biomolecules
; 10(8)2020 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32824246
19.
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib.
J Med Chem
; 63(5): 2588-2619, 2020 03 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32037829
20.
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign.
Eur J Med Chem
; 189: 112047, 2020 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31982652