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1.
Genome-wide association study of abnormal elevation of ALT in patients exposed to atabecestat.
BMC Genomics
; 24(1): 513, 2023 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37658353
2.
Targeting Progranulin as an Immuno-Neurology Therapeutic Approach.
Int J Mol Sci
; 24(21)2023 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-37958929
3.
The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable.
Alzheimers Dement
; 14(4): 563-575, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29653607
4.
Preliminary Results of a Trial of Atabecestat in Preclinical Alzheimer's Disease.
N Engl J Med
; 380(15): 1483-1485, 2019 04 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30970197
5.
Impact of cerebrospinal fluid matrix on the detection of Alzheimer's disease with Aß42 and influence of disease on the total-Aß42/Aß40 ratio.
J Neurochem
; 135(5): 1049-58, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26332787
6.
Immediate Reactions to Alzheimer Biomarker Disclosure in Cognitively Unimpaired Individuals in a Global Truncated Randomized Trial.
Neurol Clin Pract
; 14(2): e200265, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38585443
7.
Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial.
JAMA Neurol
; 78(3): 293-301, 2021 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33464300
8.
A multiple-dose double-blind randomized study to evaluate the safety, pharmacokinetics, pharmacodynamics and analgesic efficacy of the TRPV1 antagonist JNJ-39439335 (mavatrep).
Scand J Pain
; 18(2): 151-164, 2018 04 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-29794306
9.
Fulranumab in Patients With Pain Associated With Postherpetic Neuralgia and Postraumatic Neuropathy: Efficacy, Safety, and Tolerability Results From a Randomized, Double-blind, Placebo-controlled, Phase-2 Study.
Clin J Pain
; 33(2): 99-108, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27153360
10.
A randomized study to evaluate the analgesic efficacy of a single dose of the TRPV1 antagonist mavatrep in patients with osteoarthritis.
Scand J Pain
; 17: 134-143, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28850367
11.
TRPV1 antagonist JNJ-39439335 (mavatrep) demonstrates proof of pharmacology in healthy men: a first-in-human, double-blind, placebo-controlled, randomized, sequential group study.
Pain Rep
; 1(4): e576, 2016 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-29392196
12.
Safety, Tolerability and Pharmacokinetic and Pharmacodynamic Learnings from a Double-Blind, Randomized, Placebo-Controlled, Sequential Group First-in-Human Study of the TRPV1 Antagonist, JNJ-38893777, in Healthy Men.
Clin Drug Investig
; 35(6): 353-63, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-25894894
13.
SCN9A Variants May be Implicated in Neuropathic Pain Associated With Diabetic Peripheral Neuropathy and Pain Severity.
Clin J Pain
; 31(11): 976-82, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25585270
14.
Novel Statistically-Derived Composite Measures for Assessing the Efficacy of Disease-Modifying Therapies in Prodromal Alzheimer's Disease Trials: An AIBL Study.
J Alzheimers Dis
; 46(4): 1079-89, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26402634
15.
Fulranumab for treatment of diabetic peripheral neuropathic pain: A randomized controlled trial.
Neurology
; 83(7): 628-37, 2014 Aug 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-25008392
16.
Coalition Against Major Diseases: Precompetitive Collaborations and Regulatory Paths to Accelerating Drug Development for Neurodegenerative Diseases.
Ther Innov Regul Sci
; 47(6): 632-638, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-30235546
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