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1.
Selective BTK inhibition improves bendamustine therapy response and normalizes immune effector functions in chronic lymphocytic leukemia.
Int J Cancer
; 144(11): 2762-2773, 2019 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30468254
2.
Mutations in the RAS-BRAF-MAPK-ERK pathway define a specific subgroup of patients with adverse clinical features and provide new therapeutic options in chronic lymphocytic leukemia.
Haematologica
; 104(3): 576-586, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30262568
3.
The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78.
Blood
; 117(4): 1270-9, 2011 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-21106982
4.
The phosphatidylinositol-3-kinase inhibitor NVP-BKM120 overcomes resistance signals derived from microenvironment by regulating the Akt/FoxO3a/Bim axis in chronic lymphocytic leukemia cells.
Haematologica
; 98(11): 1739-47, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23850807
5.
Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia.
Sci Rep
; 10(1): 22153, 2020 12 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33335123
6.
Targeting IRAK4 disrupts inflammatory pathways and delays tumor development in chronic lymphocytic leukemia.
Leukemia
; 34(1): 100-114, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31197259
7.
Specific NOTCH1 antibody targets DLL4-induced proliferation, migration, and angiogenesis in NOTCH1-mutated CLL cells.
Oncogene
; 39(6): 1185-1197, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31616059
8.
The contributions of Paul Ehrlich to pharmacology: a tribute on the occasion of the centenary of his Nobel Prize.
Pharmacology
; 82(3): 171-9, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18679046
9.
New drug discovery approaches targeting recurrent mutations in chronic lymphocytic leukemia.
Expert Opin Drug Discov
; 12(10): 1041-1052, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28776453
10.
CD69 expression potentially predicts response to bendamustine and its modulation by ibrutinib or idelalisib enhances cytotoxic effect in chronic lymphocytic leukemia.
Oncotarget
; 7(5): 5507-20, 2016 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-26701728
11.
The splicing modulator sudemycin induces a specific antitumor response and cooperates with ibrutinib in chronic lymphocytic leukemia.
Oncotarget
; 6(26): 22734-49, 2015 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26068951
12.
Bcl-2high mantle cell lymphoma cells are sensitized to acadesine with ABT-199.
Oncotarget
; 6(25): 21159-72, 2015 Aug 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-26110568
13.
Dual PI3K/mTOR inhibition is required to effectively impair microenvironment survival signals in mantle cell lymphoma.
Oncotarget
; 5(16): 6788-800, 2014 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-25216518
14.
Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma.
Oncotarget
; 5(3): 726-39, 2014 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24519895
15.
Disruption of follicular dendritic cells-follicular lymphoma cross-talk by the pan-PI3K inhibitor BKM120 (Buparlisib).
Clin Cancer Res
; 20(13): 3458-71, 2014 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24799524
16.
Autophagy controls everolimus (RAD001) activity in mantle cell lymphoma.
Autophagy
; 9(1): 115-7, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23079699
17.
Sorafenib inhibits cell migration and stroma-mediated bortezomib resistance by interfering B-cell receptor signaling and protein translation in mantle cell lymphoma.
Clin Cancer Res
; 19(3): 586-97, 2013 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23231952
18.
Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma.
Clin Cancer Res
; 18(19): 5278-89, 2012 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22879389
19.
Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoters.
Clin Cancer Res
; 17(12): 3956-68, 2011 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21652541
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