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1.
Patient-reported outcomes and inflammatory biomarkers in patients with locally advanced/metastatic urothelial carcinoma treated with durvalumab in phase 1/2 dose-escalation study 1108.
Cancer
; 126(2): 432-443, 2020 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31581306
2.
Prevalence of IgG and Neutralizing Antibodies against Staphylococcus aureus Alpha-Toxin in Healthy Human Subjects and Diverse Patient Populations.
Infect Immun
; 86(3)2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29263109
3.
Blockade of GM-CSF pathway induced sustained suppression of myeloid and T cell activities in rheumatoid arthritis.
Rheumatology (Oxford)
; 57(1): 175-184, 2018 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29069507
4.
Quantitative measurement of the target-mediated internalization kinetics of biopharmaceuticals.
Pharm Res
; 32(1): 286-99, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25208874
5.
Suppression of soluble T cell-associated proteins by an anti-interferon-α monoclonal antibody in adult patients with dermatomyositis or polymyositis.
Rheumatology (Oxford)
; 53(4): 686-95, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24357810
6.
Population Pharmacokinetics and Exposure-Response Analysis for the Phase 3 COSMIC-311 Trial of Cabozantinib for Radioiodine-Refractory Differentiated Thyroid Cancer.
Clin Pharmacokinet
; 62(4): 587-598, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36869986
7.
Combining pharmacometric models with predictive and prognostic biomarkers for precision therapy in Crohn's disease: A case study of brazikumab.
CPT Pharmacometrics Syst Pharmacol
; 12(12): 1945-1959, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37691451
8.
Multiplex Bioanalytical Methods for Comprehensive Characterization and Quantification of the Unique Complementarity-Determining-Region Deamidation of MEDI7247, an Anti-ASCT2 Pyrrolobenzodiazepine Antibody-Drug Conjugate.
Antibodies (Basel)
; 12(4)2023 Oct 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-37873863
9.
Population pharmacokinetics of palivizumab, a humanized anti-respiratory syncytial virus monoclonal antibody, in adults and children.
Antimicrob Agents Chemother
; 56(9): 4927-36, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22802243
10.
Mechanistic modeling of a human IgG4 monoclonal antibody (tralokinumab) Fab-arm exchange with endogenous IgG4 in healthy volunteers.
CPT Pharmacometrics Syst Pharmacol
; 11(4): 438-446, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35023315
11.
Association of circulating protein biomarkers with clinical outcomes of durvalumab in head and neck squamous cell carcinoma.
Oncoimmunology
; 10(1): 1898104, 2021 03 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33796405
12.
An open-label, single-dose bioavailability study of the pharmacokinetics of CAT-354 after subcutaneous and intravenous administration in healthy males.
Br J Clin Pharmacol
; 69(6): 645-55, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20565456
13.
A novel approach to assess domain specificity of anti-drug antibodies to moxetumomab pasudotox, an immunotoxin with two functional domains.
J Immunol Methods
; 477: 112688, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31676342
14.
Molecular Mechanism of HER2 Rapid Internalization and Redirected Trafficking Induced by Anti-HER2 Biparatopic Antibody.
Antibodies (Basel)
; 9(3)2020 Sep 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-32961882
15.
A new method for identification of outliers in immunogenicity assay cut point data.
J Immunol Methods
; 484-485: 112817, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32615125
16.
Confirmatory cut point has limited ability to make accurate classifications in immunogenicity assays.
Bioanalysis
; 12(4): 245-256, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-32090586
17.
Population Pharmacokinetic Modeling of Benralizumab in Adult and Adolescent Patients with Asthma.
Clin Pharmacokinet
; 58(7): 943-958, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30854591
18.
Pharmacodynamic biomarkers and differential effects of TNF- and GM-CSF-targeting biologics in rheumatoid arthritis.
Int J Rheum Dis
; 22(4): 646-653, 2019 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-30358109
19.
Excessive outlier removal may result in cut points that are not suitable for immunogenicity assessments.
J Immunol Methods
; 463: 105-111, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30312600
20.
Selection of a Ligand-Binding Neutralizing Antibody Assay for Benralizumab: Comparison with an Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) Cell-Based Assay.
AAPS J
; 20(3): 49, 2018 03 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-29541868