Detalles de la búsqueda
1.
PCSK9 inhibition attenuates alcohol-associated neuronal oxidative stress and cellular injury.
Brain Behav Immun
; 119: 494-506, 2024 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-38657842
2.
Alcohol use disorder is associated with DNA methylation-based shortening of telomere length and regulated by TESPA1: implications for aging.
Mol Psychiatry
; 27(9): 3875-3884, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35705636
3.
Educational attainment impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study with ~780,000 participants.
Mol Psychiatry
; 26(4): 1119-1132, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31649322
4.
Epigenome-wide association study and multi-tissue replication of individuals with alcohol use disorder: evidence for abnormal glucocorticoid signaling pathway gene regulation.
Mol Psychiatry
; 26(6): 2224-2237, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32398718
5.
Evaluating the relationship between alcohol consumption, tobacco use, and cardiovascular disease: A multivariable Mendelian randomization study.
PLoS Med
; 17(12): e1003410, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33275596
6.
Adverse Childhood Experiences are Associated with High-Intensity Binge Drinking Behavior in Adulthood and Mediated by Psychiatric Disorders.
Alcohol Alcohol
; 55(2): 204-214, 2020 Mar 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-31895420
7.
Lack of Association Between Serotonin Transporter Gene (SLC6A4) Promoter Methylation and Amygdala Response During Negative Emotion Processing in Individuals With Alcohol Dependence.
Alcohol Alcohol
; 54(3): 209-215, 2019 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31008507
8.
Assessing the Impact of PCSK9 and HMGCR Inhibition on Liver Function: Drug-Target Mendelian Randomization Analyses in Four Ancestries.
Cell Mol Gastroenterol Hepatol
; 17(1): 29-40, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-37703945
9.
LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic ß cells.
Cell Rep
; 43(4): 114047, 2024 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38607916
10.
Proprotein convertase subtilisin/kexin type 9 (PCSK9) in the central nervous system.
Neurosci Biobehav Rev
; 149: 105155, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37019248
11.
Multi-omic underpinnings of epigenetic aging and human longevity.
Nat Commun
; 14(1): 2236, 2023 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-37076473
12.
Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging.
Nat Aging
; 3(8): 1020-1035, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37550455
13.
Additive Effects of Stress and Alcohol Exposure on Accelerated Epigenetic Aging in Alcohol Use Disorder.
Biol Psychiatry
; 93(4): 331-341, 2023 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36182531
14.
Association Between Brain Structure and Alcohol Use Behaviors in Adults: A Mendelian Randomization and Multiomics Study.
JAMA Psychiatry
; 79(9): 869-878, 2022 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35947372
15.
Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive Function.
J Am Coll Cardiol
; 80(7): 653-662, 2022 08 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-35953131
16.
Comparing the Relationships of Genetically Proxied PCSK9 Inhibition With Mood Disorders, Cognition, and Dementia Between Men and Women: A Drug-Target Mendelian Randomization Study.
J Am Heart Assoc
; 11(21): e026122, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36285785
17.
Smoking is significantly associated with increased risk of COVID-19 and other respiratory infections.
Commun Biol
; 4(1): 1230, 2021 10 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34711921
18.
A genetically-informed study disentangling the relationships between tobacco smoking, cannabis use, alcohol consumption, substance use disorders and respiratory infections, including COVID-19.
medRxiv
; 2021 Feb 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33594380
19.
Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis.
JAMA Psychiatry
; 78(2): 151-160, 2021 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33175090
20.
Educational attainment reduces the risk of suicide attempt among individuals with and without psychiatric disorders independent of cognition: a bidirectional and multivariable Mendelian randomization study with more than 815,000 participants.
Transl Psychiatry
; 10(1): 388, 2020 11 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33168806