Detalles de la búsqueda
1.
Drug transporters in drug disposition - the year 2022 in review.
Drug Metab Rev
; 55(4): 343-370, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37644867
2.
Novel insights in drug transporter sciences: the year 2021 in review.
Drug Metab Rev
; 54(3): 299-317, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35762758
3.
Recent advances in drug transporter sciences: highlights from the year 2020.
Drug Metab Rev
; 53(3): 321-349, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34346798
4.
The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide-Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy.
Drug Metab Dispos
; 44(5): 692-9, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26888941
5.
Toward a unified model of passive drug permeation II: the physiochemical determinants of unbound tissue distribution with applications to the design of hepatoselective glucokinase activators.
Drug Metab Dispos
; 42(10): 1599-610, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25024402
6.
Improving on nature: making a cyclic heptapeptide orally bioavailable.
Angew Chem Int Ed Engl
; 53(45): 12059-63, 2014 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-25219505
7.
Quantitative prediction of repaglinide-rifampicin complex drug interactions using dynamic and static mechanistic models: delineating differential CYP3A4 induction and OATP1B1 inhibition potential of rifampicin.
Drug Metab Dispos
; 41(5): 966-74, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23393219
8.
Quantitative prediction of renal transporter-mediated clinical drug-drug interactions.
Mol Pharm
; 10(11): 4207-15, 2013 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-24066726
9.
Discovery of an intravenous hepatoselective glucokinase activator for the treatment of inpatient hyperglycemia.
Bioorg Med Chem Lett
; 23(24): 6588-92, 2013 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24239482
10.
Elucidation of the biochemical basis for a clinical drug-drug interaction between atorvastatin and 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methyl benzoic acid (CP-778875), a subtype selective agonist of the peroxisome proliferator-activated receptor alpha.
Xenobiotica
; 43(11): 963-72, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23631744
11.
Quantitative assessment of the contribution of sodium-dependent taurocholate co-transporting polypeptide (NTCP) to the hepatic uptake of rosuvastatin, pitavastatin and fluvastatin.
Biopharm Drug Dispos
; 34(8): 452-61, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23996477
12.
pH-Dependent solubility and permeability criteria for provisional biopharmaceutics classification (BCS and BDDCS) in early drug discovery.
Mol Pharm
; 9(5): 1199-212, 2012 May 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-22489626
13.
Current Approaches for Predicting Human PK for Small Molecule Development Candidates: Findings from the IQ Human PK Prediction Working Group Survey.
AAPS J
; 24(5): 85, 2022 07 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35854202
14.
pH-sensitive interaction of HMG-CoA reductase inhibitors (statins) with organic anion transporting polypeptide 2B1.
Mol Pharm
; 8(4): 1303-13, 2011 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21710988
15.
Refining the in vitro and in vivo critical parameters for P-glycoprotein, [I]/IC50 and [I2]/IC50, that allow for the exclusion of drug candidates from clinical digoxin interaction studies.
Mol Pharm
; 7(2): 398-411, 2010 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-20025245
16.
Effect of chitosan glutamate, carbomer 974P, and EDTA on the in vitro Caco-2 permeability and oral pharmacokinetic profile of acyclovir in rats.
Drug Dev Ind Pharm
; 35(9): 1082-91, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19294548
17.
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results.
Eur J Pharm Sci
; 96: 610-625, 2017 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27816631
18.
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes.
Eur J Pharm Sci
; 96: 626-642, 2017 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27693299
19.
Mechanism-based pharmacokinetic modeling to evaluate transporter-enzyme interplay in drug interactions and pharmacogenetics of glyburide.
AAPS J
; 16(4): 736-48, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24839071
20.
Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed.
ACS Med Chem Lett
; 5(10): 1148-51, 2014 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-25313329