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1.
XEN-D0501, a Novel Transient Receptor Potential Vanilloid 1 Antagonist, Does Not Reduce Cough in Patients with Refractory Cough.
Am J Respir Crit Care Med
; 196(10): 1255-1263, 2017 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28650204
2.
Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial.
Lancet
; 386(9992): 452-60, 2015 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26047975
3.
Tolerability, pharmacokinetics and pharmacodynamics of TA-8995, a selective cholesteryl ester transfer protein (CETP) inhibitor, in healthy subjects.
Br J Clin Pharmacol
; 78(3): 498-508, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24628035
4.
Use of continuous ECG for improvements in assessing the standing response as a positive control for QT prolongation.
Ann Noninvasive Electrocardiol
; 19(1): 82-9, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24460808
5.
An investigation of the safety and pharmacokinetics of the novel TRPV1 antagonist XEN-D0501 in healthy subjects.
Br J Clin Pharmacol
; 72(6): 921-31, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21676011
6.
A double-blind, randomised, placebo-controlled, cross-over study assessing the use of XEN-D0103 in patients with paroxysmal atrial fibrillation and implanted pacemakers allowing continuous beat-to-beat monitoring of drug efficacy.
J Interv Card Electrophysiol
; 51(3): 191-197, 2018 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-29460236
7.
The positive frequency-dependent electrophysiological effects of the IKur inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation.
Heart Rhythm
; 13(2): 555-64, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26455450
8.
Effects of the cholesteryl ester transfer protein inhibitor, TA-8995, on cholesterol efflux capacity and high-density lipoprotein particle subclasses.
J Clin Lipidol
; 10(5): 1137-1144.e3, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27678430
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