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1.
CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors.
Proc Natl Acad Sci U S A
; 108(40): 16663-8, 2011 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-21930917
2.
Activation of HIF-1alpha in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway.
J Cell Physiol
; 218(1): 167-74, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18781596
3.
Extracellular signal-regulated kinases phosphorylate mitogen-activated protein kinase phosphatase 3/DUSP6 at serines 159 and 197, two sites critical for its proteasomal degradation.
Mol Cell Biol
; 25(2): 854-64, 2005 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-15632084
4.
The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
Cancer Res
; 66(7): 3688-98, 2006 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16585195
5.
AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of Ras-transformed fibroblasts.
Oncotarget
; 6(14): 11833-47, 2015 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-26059436
6.
Genetic disruption of lactate/H+ symporters (MCTs) and their subunit CD147/BASIGIN sensitizes glycolytic tumor cells to phenformin.
Cancer Res
; 75(1): 171-80, 2015 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25403912
7.
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains.
Mol Cell Biol
; 29(10): 2570-81, 2009 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-19273585
8.
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.
EMBO J
; 22(16): 4082-90, 2003 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12912907
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