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1.
Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes.
J Enzyme Inhib Med Chem
; 37(1): 515-526, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35144520
2.
1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3ß.
Bioorg Med Chem
; 32: 115998, 2021 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33440320
3.
Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni: Structural and Mechanistic Insights into Chemotype Reactivity.
ACS Infect Dis
; 7(1): 189-201, 2021 01 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33301315
4.
Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors.
ACS Infect Dis
; 7(5): 1077-1088, 2021 05 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33175511
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