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1.
Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.
Nat Genet
; 18(2): 126-35, 1998 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-9462740
2.
PIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemia.
Mol Cell Biol
; 19(7): 5170-8, 1999 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-10373566
3.
Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.
Mol Cell Biol
; 17(8): 4859-69, 1997 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-9234742
4.
BCR-ABL mediates arsenic trioxide-induced apoptosis independently of its aberrant kinase activity.
Cancer Res
; 60(13): 3409-13, 2000 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-10910048
5.
The acute promyelocytic leukaemia specific PML and PLZF proteins localize to adjacent and functionally distinct nuclear bodies.
Oncogene
; 16(15): 1945-53, 1998 Apr 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-9591778
6.
Acute promyelocytic leukemia: PML/RARalpha and the leukemic stem cell.
Leukemia
; 18(7): 1169-75, 2004 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15103387
7.
PF-114, a potent and selective inhibitor of native and mutated BCR/ABL is active against Philadelphia chromosome-positive (Ph+) leukemias harboring the T315I mutation.
Leukemia
; 29(5): 1104-14, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25394714
8.
Down-stream regions of the POZ-domain influence the interaction of the t(11;17)-associated PLZF/RARalpha fusion protein with the histone-deacetylase recruiting co-repressor complex.
Hematol J
; 2(6): 385-92, 2001.
Artículo
en Inglés
| MEDLINE | ID: mdl-11920278
9.
Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia.
Hematol J
; 2(2): 103-7, 2001.
Artículo
en Inglés
| MEDLINE | ID: mdl-11424002
10.
The t(6;9) associated DEK/CAN fusion protein targets a population of long-term repopulating hematopoietic stem cells for leukemogenic transformation.
Leukemia
; 24(11): 1910-9, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20827285
11.
Oligomerization inhibition, combined with allosteric inhibition, abrogates the transformation potential of T315I-positive BCR/ABL.
Leukemia
; 23(12): 2242-7, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19798092
12.
The gatekeeper mutation T315I confers resistance against small molecules by increasing or restoring the ABL-kinase activity accompanied by aberrant transphosphorylation of endogenous BCR, even in loss-of-function mutants of BCR/ABL.
Leukemia
; 23(9): 1614-21, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19369965
13.
Suppression of the DNA damage response in acute myeloid leukemia versus myelodysplastic syndrome.
Oncogene
; 28(22): 2205-18, 2009 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-19398952
14.
Developmental analysis of murine Promyelocyte Leukemia Zinc Finger (PLZF) gene expression: implications for the neuromeric model of the forebrain organization.
J Neurosci
; 15(7 Pt 1): 4927-42, 1995 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-7623123
15.
Characterization of the retinoid binding properties of the major fusion products present in acute promyelocytic leukemia cells.
Blood
; 90(3): 1175-85, 1997 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-9242550
16.
Caspases mediate retinoic acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion protein.
Blood
; 92(7): 2244-51, 1998 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-9746761
17.
Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia.
Nature
; 391(6669): 815-8, 1998 Feb 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-9486655
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