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1.
Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity.
Proc Natl Acad Sci U S A
; 112(11): E1297-306, 2015 Mar 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-25733881
2.
The pathogenic Th17 cell response to major schistosome egg antigen is sequentially dependent on IL-23 and IL-1ß.
J Immunol
; 187(10): 5328-35, 2011 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22003203
3.
Exacerbated egg-induced immunopathology in murine Schistosoma mansoni infection is primarily mediated by IL-17 and restrained by IFN-γ.
Eur J Immunol
; 41(9): 2677-87, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21660933
4.
Genetic control of severe egg-induced immunopathology and IL-17 production in murine schistosomiasis.
J Immunol
; 183(5): 3317-23, 2009 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19675160
5.
T-bet protects against exacerbation of schistosome egg-induced immunopathology by regulating Th17-mediated inflammation.
Eur J Immunol
; 39(9): 2470-81, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19714576
6.
Dendritic cell IL-23 and IL-1 production in response to schistosome eggs induces Th17 cells in a mouse strain prone to severe immunopathology.
J Immunol
; 181(12): 8559-67, 2008 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19050275
7.
Coinfection with the intestinal nematode Heligmosomoides polygyrus markedly reduces hepatic egg-induced immunopathology and proinflammatory cytokines in mouse models of severe schistosomiasis.
Infect Immun
; 76(11): 5164-72, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18710859
8.
Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors.
Sci Transl Med
; 8(365): 365ra158, 2016 11 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-27856797
9.
Induction and regulation of pathogenic Th17 cell responses in schistosomiasis.
Semin Immunopathol
; 34(6): 873-88, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23096253
10.
IL-23 is required for the development of severe egg-induced immunopathology in schistosomiasis and for lesional expression of IL-17.
J Immunol
; 180(4): 2486-95, 2008 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18250458
11.
Disruption of interleukin-27 signaling results in impaired gamma interferon production but does not significantly affect immunopathology in murine schistosome infection.
Infect Immun
; 75(6): 3169-77, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17403877
12.
Protective immune mechanisms in helminth infection.
Nat Rev Immunol
; 7(12): 975-87, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18007680
13.
CD4 T cells producing pro-inflammatory interleukin-17 mediate high pathology in schistosomiasis.
Mem Inst Oswaldo Cruz
; 101 Suppl 1: 327-30, 2006 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17308791
14.
Severe CD4 T cell-mediated immunopathology in murine schistosomiasis is dependent on IL-12p40 and correlates with high levels of IL-17.
J Immunol
; 175(6): 3920-6, 2005 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16148138
15.
Enhanced egg-induced immunopathology correlates with high IFN-gamma in murine schistosomiasis: identification of two epistatic genetic intervals.
J Immunol
; 174(1): 435-40, 2005 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15611268
16.
Apoptosis by neglect of CD4+ Th cells in granulomas: a novel effector mechanism involved in the control of egg-induced immunopathology in murine schistosomiasis.
J Immunol
; 171(4): 1859-67, 2003 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12902487
17.
IL-10 is crucial for the transition from acute to chronic disease state during infection of mice with Schistosoma mansoni.
Eur J Immunol
; 33(4): 880-8, 2003 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-12672053
18.
Disruption of the ICOS-B7RP-1 costimulatory pathway leads to enhanced hepatic immunopathology and increased gamma interferon production by CD4 T cells in murine schistosomiasis.
Infect Immun
; 71(7): 4040-4, 2003 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12819093
19.
Diminished immunopathology in Schistosoma mansoni infection following intranasal administration of cholera toxin B-immunodominant peptide conjugate correlates with enhanced transforming growth factor-beta production by CD4 T cells.
Parasite Immunol
; 24(8): 423-7, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12406196
20.
The immunobiology of Th1 polarization in high-pathology schistosomiasis.
Immunol Rev
; 201: 168-79, 2004 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15361240