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1.
Solution Thermodynamics and Kinetics of Metal Complexation with a Hydroxypyridinone Chelator Designed for Thorium-227 Targeted Alpha Therapy.
Inorg Chem
; 57(22): 14337-14346, 2018 Nov 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-30372069
2.
Development of separation technology for the removal of radium-223 from targeted thorium conjugate formulations. Part I: purification of decayed thorium-227 on cation exchange columns.
Drug Dev Ind Pharm
; 43(2): 225-233, 2017 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-27628177
3.
Development of separation technology for the removal of radium-223 from targeted thorium conjugate formulations. Part II: purification of targeted thorium conjugates on cation exchange columns.
Drug Dev Ind Pharm
; 43(9): 1440-1449, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28402142
4.
An efficient chelator for complexation of thorium-227.
Bioorg Med Chem Lett
; 26(17): 4318-21, 2016 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27476138
5.
Development of separation technology for the removal of radium-223 from decayed thorium-227 in drug formulations. Material screening and method development.
Drug Dev Ind Pharm
; 42(8): 1215-24, 2016 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26569601
6.
Efficacy of a HER2-Targeted Thorium-227 Conjugate in a HER2-Positive Breast Cancer Bone Metastasis Model.
Cancers (Basel)
; 15(13)2023 Jun 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-37444529
7.
Advances in Precision Oncology: Targeted Thorium-227 Conjugates As a New Modality in Targeted Alpha Therapy.
Cancer Biother Radiopharm
; 35(7): 497-510, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32255671
8.
Preclinical Efficacy of a PSMA-Targeted Thorium-227 Conjugate (PSMA-TTC), a Targeted Alpha Therapy for Prostate Cancer.
Clin Cancer Res
; 26(8): 1985-1996, 2020 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31831560
9.
Synergistic Effect of a HER2 Targeted Thorium-227 Conjugate in Combination with Olaparib in a BRCA2 Deficient Xenograft Model.
Pharmaceuticals (Basel)
; 12(4)2019 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31618864
10.
Synergistic Effect of a Mesothelin-Targeted 227Th Conjugate in Combination with DNA Damage Response Inhibitors in Ovarian Cancer Xenograft Models.
J Nucl Med
; 60(9): 1293-1300, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30850485
11.
Preclinical Combination Studies of an FGFR2 Targeted Thorium-227 Conjugate and the ATR Inhibitor BAY 1895344.
Int J Radiat Oncol Biol Phys
; 105(2): 410-422, 2019 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31255687
12.
Mesothelin-Targeted Thorium-227 Conjugate (MSLN-TTC): Preclinical Evaluation of a New Targeted Alpha Therapy for Mesothelin-Positive Cancers.
Clin Cancer Res
; 25(15): 4723-4734, 2019 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31064781
13.
In Vitro and In Vivo Efficacy of a Novel CD33-Targeted Thorium-227 Conjugate for the Treatment of Acute Myeloid Leukemia.
Mol Cancer Ther
; 15(10): 2422-2431, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27535972
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