Detalles de la búsqueda
1.
Novel potent dual inhibitors of CK2 and Pim kinases with antiproliferative activity against cancer cells.
Bioorg Med Chem Lett
; 22(9): 3327-31, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22460033
2.
Synthesis and SAR of inhibitors of protein kinase CK2: novel tricyclic quinoline analogs.
Bioorg Med Chem Lett
; 22(1): 45-8, 2012 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22169261
3.
Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer.
Biochemistry
; 50(39): 8478-88, 2011 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-21870818
4.
Protein kinase CK2 modulates IL-6 expression in inflammatory breast cancer.
Biochem Biophys Res Commun
; 415(1): 163-7, 2011 Nov 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-22027148
5.
Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer.
Mol Cell Biochem
; 356(1-2): 37-43, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21755459
6.
Novel potent pyrimido[4,5-c]quinoline inhibitors of protein kinase CK2: SAR and preliminary assessment of their analgesic and anti-viral properties.
Bioorg Med Chem Lett
; 21(6): 1687-91, 2011 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21316963
7.
7-(4H-1,2,4-Triazol-3-yl)benzo[c][2,6]naphthyridines: a novel class of Pim kinase inhibitors with potent cell antiproliferative activity.
Bioorg Med Chem Lett
; 21(22): 6687-92, 2011 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21982499
8.
Assessment and Development of the Antifungal Agent Caspofungin for Aerosolized Pulmonary Delivery.
Pharmaceutics
; 13(4)2021 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33916988
9.
Pharmacokinetic and Pharmacodynamic Comparison of Intravenous and Inhaled Caspofungin.
J Aerosol Med Pulm Drug Deliv
; 34(3): 197-203, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32985935
10.
A prodrug approach toward the development of water soluble fluoroquinolones and structure--activity relationships of quinoline-3-carboxylic acids.
J Med Chem
; 47(19): 4693-709, 2004 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-15341485
11.
CK2 inhibitor CX-4945 suppresses DNA repair response triggered by DNA-targeted anticancer drugs and augments efficacy: mechanistic rationale for drug combination therapy.
Mol Cancer Ther
; 11(4): 994-1005, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22267551
12.
Combined inhibition of EGFR and CK2 augments the attenuation of PI3K-Akt-mTOR signaling and the killing of cancer cells.
Cancer Lett
; 322(1): 113-8, 2012 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22387988
13.
Discovery of CX-6258. A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor.
ACS Med Chem Lett
; 3(2): 135-9, 2012 Feb 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900437
14.
Discovery of CX-5461, the First Direct and Selective Inhibitor of RNA Polymerase I, for Cancer Therapeutics.
ACS Med Chem Lett
; 3(7): 602-6, 2012 Jul 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900516
15.
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Cancer Cell
; 22(1): 51-65, 2012 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-22789538
16.
Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.
Cancer Res
; 71(4): 1418-30, 2011 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21159662
17.
Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CX-4945), the first clinical stage inhibitor of protein kinase CK2 for the treatment of cancer.
J Med Chem
; 54(2): 635-54, 2011 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-21174434
18.
CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy.
Cancer Res
; 70(24): 10288-98, 2010 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21159648
19.
Potential use of selective and nonselective Pim kinase inhibitors for cancer therapy.
J Med Chem
; 55(19): 8199-208, 2012 Oct 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-22924342
Resultados
1 -
19
de 19
1
Próxima >
>>