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1.
Contribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo Outcomes.
Drug Metab Dispos
; 44(3): 466-75, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26684498
2.
Nevirapine extended-release formulation tablets in HIV-1-infected children--long-term follow-up.
Clin Infect Dis
; 61(3): 476-9, 2015 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25917636
3.
Effect of the hepatitis C virus protease inhibitor faldaprevir on the pharmacokinetics of an oral contraceptive containing ethinylestradiol and levonorgestrel in healthy female volunteers.
Antimicrob Agents Chemother
; 59(1): 514-9, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25385099
4.
Mass balance, metabolite profile, and in vitro-in vivo comparison of clearance pathways of deleobuvir, a hepatitis C virus polymerase inhibitor.
Antimicrob Agents Chemother
; 59(1): 25-37, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25313217
5.
Efficacy and safety of faldaprevir, deleobuvir, and ribavirin in treatment-naive patients with chronic hepatitis C virus infection and advanced liver fibrosis or cirrhosis.
Antimicrob Agents Chemother
; 59(2): 1282-91, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25512403
6.
Clinical assessment of potential drug interactions of faldaprevir, a hepatitis C virus protease inhibitor, with darunavir/ritonavir, efavirenz, and tenofovir.
Clin Infect Dis
; 59(10): 1420-8, 2014 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25091302
7.
Lack of a pharmacokinetic interaction between steady-state tipranavir/ritonavir and single-dose valacyclovir in healthy volunteers.
Eur J Clin Pharmacol
; 67(3): 277-81, 2011 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20963404
8.
Pharmacokinetic characterization of three doses of tipranavir boosted with ritonavir on highly active antiretroviral therapy in treatment-experienced HIV-1 patients.
HIV Clin Trials
; 11(1): 28-38, 2010.
Artículo
en Inglés
| MEDLINE | ID: mdl-20400409
9.
Interaction studies of tipranavir-ritonavir with clarithromycin, fluconazole, and rifabutin in healthy volunteers.
Antimicrob Agents Chemother
; 53(1): 162-73, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19015362
10.
Pharmacokinetic Interaction between Faldaprevir and Cyclosporine or Tacrolimus in Healthy Volunteers: A Prospective, Open-Label, Fixed-Sequence, Crossover Study.
Basic Clin Pharmacol Toxicol
; 123(1): 84-93, 2018 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-29427400
11.
Combined tipranavir and enfuvirtide use associated with higher plasma tipranavir concentrations but not with increased hepatotoxicity: sub-analysis from RESIST.
AIDS
; 21(14): 1977-80, 2007 Sep 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-17721109
12.
Pharmacokinetic analysis of nevirapine extended release 400 mg once daily vs nevirapine immediate release 200 mg twice daily formulation in treatment-naïve patients with HIV-1 infection.
HIV Clin Trials
; 18(5-6): 189-195, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-29210627
13.
Interactions of the hepatitis C virus protease inhibitor faldaprevir with cytochrome P450 enzymes: in vitro and in vivo correlation.
J Clin Pharmacol
; 55(4): 467-77, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25449227
14.
Pharmacokinetic characterization of different dose combinations of coadministered tipranavir and ritonavir in healthy volunteers.
HIV Clin Trials
; 5(6): 371-82, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15682350
15.
Steady-state pharmacokinetics of nevirapine extended-release tablets in HIV-1-infected children and adolescents: an open-label, multiple-dose, cross-over study.
Pediatr Infect Dis J
; 33(7): e173-9, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24378938
16.
Effects of tipranavir, darunavir, and ritonavir on platelet function, coagulation, and fibrinolysis in healthy volunteers.
Curr HIV Res
; 9(4): 237-46, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21671884
17.
Pharmacokinetic interactions between buprenorphine/naloxone and tipranavir/ritonavir in HIV-negative subjects chronically receiving buprenorphine/naloxone.
Drug Alcohol Depend
; 105(3): 234-9, 2009 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19726139
18.
Steady-state disposition of the nonpeptidic protease inhibitor tipranavir when coadministered with ritonavir.
Antimicrob Agents Chemother
; 51(7): 2436-44, 2007 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-17485497
19.
Interaction of ritonavir-boosted tipranavir with loperamide does not result in loperamide-associated neurologic side effects in healthy volunteers.
Antimicrob Agents Chemother
; 49(12): 4903-10, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16304151
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