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1.
Development of the Safe and Broad-Spectrum Aldehyde and Ketoamide Mpro inhibitors Derived from the Constrained α, γ-AA Peptide Scaffold.
Chemistry
; 29(35): e202300476, 2023 Jun 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36920943
2.
Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity.
J Am Chem Soc
; 143(49): 20697-20709, 2021 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34860011
3.
Expedited Approach toward the Rational Design of Noncovalent SARS-CoV-2 Main Protease Inhibitors.
J Med Chem
; 65(4): 2848-2865, 2022 02 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-33891389
4.
Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and FlipGFP-based reporter assay.
bioRxiv
; 2021 Mar 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-33758866
5.
Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay.
ACS Cent Sci
; 7(7): 1245-1260, 2021 Jul 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34341772
6.
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.
Cell Res
; 30(8): 678-692, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32541865
7.
Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against Mpro and cathepsin L.
bioRxiv
; 2020 Jul 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-32766590
8.
Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against Mpro and cathepsin L.
Sci Adv
; 6(50)2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33158912
9.
The P132H mutation in the main protease of Omicron SARS-CoV-2 decreases thermal stability without compromising catalysis or small-molecule drug inhibition.
Cell Res
; 32(5): 498-500, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35292745
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