Detalles de la búsqueda
1.
Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology.
Regul Toxicol Pharmacol
; 125: 105020, 2021 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-34333066
2.
Development of the Adverse Outcome Pathway (AOP): Chronic binding of antagonist to N-methyl-d-aspartate receptors (NMDARs) during brain development induces impairment of learning and memory abilities of children.
Toxicol Appl Pharmacol
; 354: 153-175, 2018 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29524501
3.
Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods.
Toxicol Appl Pharmacol
; 354: 7-18, 2018 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29476865
4.
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes.
Toxicol Appl Pharmacol
; 354: 3-6, 2018 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29447839
5.
Finding synergies for 3Rs - Toxicokinetics and read-across: Report from an EPAA partners' Forum.
Regul Toxicol Pharmacol
; 99: 5-21, 2018 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-30144470
6.
The adverse outcome pathway concept: A basis for developing regulatory decision-making tools.
Altern Lab Anim
; 44(5): 417-429, 2016 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-27805824
7.
Putative adverse outcome pathways relevant to neurotoxicity.
Crit Rev Toxicol
; 45(1): 83-91, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25605028
8.
Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence.
Regul Toxicol Pharmacol
; 72(3): 514-37, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25863193
9.
Mechanistic Understanding of the Olfactory Neuroepithelium Involvement Leading to Short-Term Anosmia in COVID-19 Using the Adverse Outcome Pathway Framework.
Cells
; 11(19)2022 09 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-36230989
10.
Development of an adverse outcome pathway for radiation-induced microcephaly via expert consultation and machine learning.
Int J Radiat Biol
; 98(12): 1752-1762, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35947014
11.
The Adverse Outcome Pathway Framework Applied to Neurological Symptoms of COVID-19.
Cells
; 11(21)2022 10 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36359807
12.
Current status and future directions for a neurotoxicity hazard assessment framework that integrates in silico approaches.
Comput Toxicol
; 222022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35844258
13.
COVID-19 through Adverse Outcome Pathways: Building networks to better understand the disease - 3rd CIAO AOP Design Workshop.
ALTEX
; 39(2): 322335, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35032963
14.
Toward a Better Testing Paradigm for Developmental Neurotoxicity: OECD Efforts and Regulatory Considerations.
Biology (Basel)
; 10(2)2021 Jan 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-33498772
15.
Gaining acceptance in next generation PBK modelling approaches for regulatory assessments - An OECD international effort.
Comput Toxicol
; 18: 100163, 2021 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-34027244
16.
The potential of mechanistic information organised within the AOP framework to increase regulatory uptake of the developmental neurotoxicity (DNT) in vitro battery of assays.
Reprod Toxicol
; 103: 159-170, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34147625
17.
Systematic Organization of COVID-19 Data Supported by the Adverse Outcome Pathway Framework.
Front Public Health
; 9: 638605, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34095051
18.
Understanding COVID-19 through adverse outcome pathways - 2nd CIAO AOP Design Workshop.
ALTEX
; 38(2): 351-357, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33677612
19.
Bringing together scientific disciplines for collaborative undertakings: a vision for advancing the adverse outcome pathway framework.
Int J Radiat Biol
; 97(4): 431-441, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33539251
20.
25th anniversary of the Berlin workshop on developmental toxicology: DevTox database update, challenges in risk assessment of developmental neurotoxicity and alternative methodologies in bone development and growth.
Reprod Toxicol
; 100: 155-162, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33278556