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1.
Relative bioavailability of ertugliflozin tablets containing the amorphous form versus tablets containing the cocrystal form.
Int J Clin Pharmacol Ther
; 60(7): 317-326, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35575420
2.
A PK/PD study comparing twice-daily to once-daily dosing regimens of ertugliflozin in healthy subjectsâ©.
Int J Clin Pharmacol Ther
; 57(4): 207-216, 2019 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-30802200
3.
Drug metabolism and drug interactions: potential application to antituberculosis drugs.
J Infect Dis
; 211 Suppl 3: S107-14, 2015 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26009614
4.
Simulating Healthy Participant Pharmacokinetics for Renal and Hepatic Impairment Studies: Retrospective Assessment of the Approach.
AAPS J
; 26(4): 65, 2024 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38844719
5.
Proposing a framework to quantify the potential impact of pharmacokinetic drug-drug interactions caused by a new drug candidate by using real world data about the target patient population.
Clin Transl Sci
; 17(3): e13741, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38445532
6.
Time to Rethink the Current Paradigm for Assessing Kidney Function in Drug Development and Beyond.
Clin Pharmacol Ther
; 112(5): 946-958, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34800044
7.
The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism.
J Transl Med
; 9: 180, 2011 Oct 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-22017794
8.
Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution.
Bioorg Med Chem Lett
; 21(9): 2725-31, 2011 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21183342
9.
Physiologically-Based Pharmacokinetic Modeling of the Drug-Drug Interaction of the UGT Substrate Ertugliflozin Following Co-Administration with the UGT Inhibitor Mefenamic Acid.
CPT Pharmacometrics Syst Pharmacol
; 10(2): 127-136, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33314761
10.
Pharmacokinetics and Pharmacodynamics of Ertugliflozin in Healthy Japanese and Western Subjects.
Clin Pharmacol Drug Dev
; 10(7): 765-776, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33434408
11.
Population pharmacokinetics and exposure-response analyses of varenicline in adolescent smokers.
CPT Pharmacometrics Syst Pharmacol
; 10(7): 769-781, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34062053
12.
Population Pharmacokinetic Analyses of Ertugliflozin in Select Ethnic Populations.
Clin Pharmacol Drug Dev
; 10(11): 1297-1306, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34213819
13.
Population Pharmacokinetic Model for Ertugliflozin in Healthy Subjects and Patients With Type 2 Diabetes Mellitus.
Clin Pharmacol Drug Dev
; 10(7): 696-706, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33205593
14.
Defining Clinically Relevant Target Populations Using Real-World Data to Guide the Design of Representative Antidiabetic Drug Trials.
Clin Pharmacol Ther
; 109(5): 1219-1223, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33615445
15.
End-to-end application of model-informed drug development for ertugliflozin, a novel sodium-glucose cotransporter 2 inhibitor.
CPT Pharmacometrics Syst Pharmacol
; 10(6): 529-542, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33932126
16.
Bioequivalence of Metformin in Ertugliflozin/Metformin Fixed-Dose Combination Tablets to Canadian-Sourced Metformin Coadministered With Ertugliflozin Under Fasted and Fed States.
Clin Pharmacol Drug Dev
; 10(5): 510-520, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33135865
17.
Meta-Analysis of Noncompartmental Pharmacokinetic Parameters of Ertugliflozin to Evaluate Dose Proportionality and UGT1A9 Polymorphism Effect on Exposure.
J Clin Pharmacol
; 61(9): 1220-1231, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33813736
18.
Pharmacokinetic Properties of Single and Multiple Doses of Ertugliflozin, a Selective Inhibitor of SGLT2, in Healthy Chinese Subjects.
Clin Pharmacol Drug Dev
; 9(1): 97-106, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30934166
19.
Overview of the Clinical Pharmacology of Ertugliflozin, a Novel Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor.
Clin Pharmacokinet
; 59(8): 949-965, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32337660
20.
Bioequivalence of Ertugliflozin/Metformin Fixed-Dose Combination Tablets and Coadministration of Respective Strengths of Individual Components.
Clin Pharmacol Drug Dev
; 9(1): 50-61, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31207178