Detalles de la búsqueda
1.
Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation.
J Lipid Res
; 56(1): 70-80, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25395359
2.
Requirements for pseudosubstrate arginine residues during autoinhibition and phosphatidylinositol 3,4,5-(PO4)3-dependent activation of atypical PKC.
J Biol Chem
; 289(36): 25021-30, 2014 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-25035426
3.
Metformin action in human hepatocytes: coactivation of atypical protein kinase C alters 5'-AMP-activated protein kinase effects on lipogenic and gluconeogenic enzyme expression.
Diabetologia
; 56(11): 2507-16, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23933835
4.
Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer.
Cancer Cell
; 8(2): 155-67, 2005 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16098468
5.
Atypical protein kinase C in cardiometabolic abnormalities.
Curr Opin Lipidol
; 23(3): 175-181, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22449812
6.
Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.
Cell Metab
; 6(1): 69-78, 2007 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-17618857
7.
Mechanisms for increased insulin-stimulated Akt phosphorylation and glucose uptake in fast- and slow-twitch skeletal muscles of calorie-restricted rats.
Am J Physiol Endocrinol Metab
; 300(6): E966-78, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21386065
8.
Roles of hepatic atypical protein kinase C hyperactivity and hyperinsulinemia in insulin-resistant forms of obesity and type 2 diabetes mellitus.
MedComm (2020)
; 2(1): 3-16, 2021 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-34766133
9.
Control of ß-Site Amyloid Precursor Protein-Cleaving Enzyme-1 Expression by Protein Kinase C-λ/ι and Nuclear Factor κ-B.
Curr Alzheimer Res
; 18(12): 941-955, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34951366
10.
Metabolic functions of atypical protein kinase C: "good" and "bad" as defined by nutritional status.
Am J Physiol Endocrinol Metab
; 298(3): E385-94, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19996389
11.
Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes.
J Clin Invest
; 117(8): 2289-301, 2007 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-17641777
12.
Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance.
Cell Signal
; 43: 62-70, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29269047
13.
Atypical PKC, PKCλ/ι, activates ß-secretase and increases Aß1-40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheimer's disease.
Neurobiol Aging
; 61: 225-237, 2018 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29032894
14.
Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity.
Diabetes
; 66(4): 920-934, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28073831
15.
Compensation for PKMζ in long-term potentiation and spatial long-term memory in mutant mice.
Elife
; 52016 05 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-27187150
16.
Role of adipocyte-derived factors in enhancing insulin signaling in skeletal muscle and white adipose tissue of mice lacking Acyl CoA:diacylglycerol acyltransferase 1.
Diabetes
; 53(6): 1445-51, 2004 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15161747
17.
Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise.
Diabetes
; 52(8): 1926-34, 2003 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12882907
18.
Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota.
Diabetes
; 51(10): 2936-43, 2002 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-12351430
19.
Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): actions and defects in obesity and type II diabetes.
Exp Biol Med (Maywood)
; 230(9): 593-605, 2005 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-16179727
20.
Tissue-specific differences in activation of atypical protein kinase C and protein kinase B in muscle, liver, and adipocytes of insulin receptor substrate-1 knockout mice.
Mol Endocrinol
; 18(10): 2513-21, 2004 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15256535