Detalles de la búsqueda
1.
Synthesis and kinetic evaluation of phosphomimetic inhibitors targeting type B ribose-5-phosphate isomerase from Mycobacterium tuberculosis.
Bioorg Med Chem Lett
; 102: 129666, 2024 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38382679
2.
Calibration of the dianionic phosphate group: Validation on the recognition site of the homodimeric enzyme phosphoglucose isomerase.
J Comput Chem
; 41(8): 839-854, 2020 03 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-31909840
3.
Novel N-substituted 5-phosphate-d-arabinonamide derivatives as strong inhibitors of phosphoglucose isomerases: Synthesis, structure-activity relationship and crystallographic studies.
Bioorg Chem
; 102: 104048, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32682158
4.
Structural basis for competitive inhibition of 3,4-dihydroxy-2-butanone-4-phosphate synthase from Vibrio cholerae.
J Biol Chem
; 290(18): 11293-308, 2015 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25792735
5.
Complexes of a Zn-metalloenzyme binding site with hydroxamate-containing ligands. A case for detailed benchmarkings of polarizable molecular mechanics/dynamics potentials when the experimental binding structure is unknown.
J Comput Chem
; 37(32): 2770-2782, 2016 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27699809
6.
Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum.
Biochem J
; 449(1): 175-87, 2013 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23039077
7.
Synthesis and evaluation of malonate-based inhibitors of phosphosugar-metabolizing enzymes: class II fructose-1,6-bis-phosphate aldolases, type I phosphomannose isomerase, and phosphoglucose isomerase.
Bioorg Med Chem
; 20(4): 1511-20, 2012 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22269276
8.
The reaction mechanism of type I phosphomannose isomerases: new information from inhibition and polarizable molecular mechanics studies.
Proteins
; 79(1): 203-20, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21058398
9.
Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase.
Acta Crystallogr D Biol Crystallogr
; 66(Pt 8): 934-44, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20693693
10.
Synthesis and evaluation of non-hydrolyzable D-mannose 6-phosphate surrogates reveal 6-deoxy-6-dicarboxymethyl-D-mannose as a new strong inhibitor of phosphomannose isomerases.
Bioorg Med Chem
; 17(20): 7100-7, 2009 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19783448
11.
Speciation of europium (III) surface species on monocrystalline alumina using time-resolved laser-induced fluorescence-scanning near-field optical microscopy.
Appl Spectrosc
; 62(2): 213-9, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18284798
12.
Ribose 5-phosphate isomerase type B from Trypanosoma cruzi: kinetic properties and site-directed mutagenesis reveal information about the reaction mechanism.
Biochem J
; 401(1): 279-85, 2007 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16981853
13.
Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase.
J Med Chem
; 61(23): 10558-10572, 2018 12 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-30418024
14.
Crystal structure of phosphomannose isomerase from Candida albicans complexed with 5-phospho-d-arabinonhydrazide.
FEBS Lett
; 592(10): 1667-1680, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29687459
15.
Carbohydrate-based electrochemical biosensor for detection of a cancer biomarker in human plasma.
Biosens Bioelectron
; 96: 178-185, 2017 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28500945
16.
The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J Mol Biol
; 343(3): 649-57, 2004 Oct 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-15465052
17.
Polarizable water networks in ligand-metalloprotein recognition. Impact on the relative complexation energies of Zn-dependent phosphomannose isomerase with D-mannose 6-phosphate surrogates.
J Phys Chem B
; 115(25): 8304-16, 2011 Jun 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-21650197
18.
Competitive inhibitors of type B ribose 5-phosphate isomerases: design, synthesis and kinetic evaluation of new D-allose and D-allulose 6-phosphate derivatives.
Carbohydr Res
; 344(7): 869-80, 2009 May 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-19328460
19.
D-ribose-5-phosphate isomerase B from Escherichia coli is also a functional D-allose-6-phosphate isomerase, while the Mycobacterium tuberculosis enzyme is not.
J Mol Biol
; 382(3): 667-79, 2008 Oct 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-18640127
20.
Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
J Mol Biol
; 379(2): 357-71, 2008 May 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-18448118