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1.
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.
Bioorg Med Chem
; 22(18): 5097-109, 2014 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24398384
2.
Synthesis and biological evaluation of 2-substituted-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents.
Bioorg Med Chem
; 20(24): 7083-94, 2012 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23117171
3.
Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1-yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A1 adenosine receptor.
Bioorg Med Chem
; 20(2): 996-1007, 2012 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22182575
4.
In silico pharmacology for a multidisciplinary drug discovery process.
Drug Metabol Drug Interact
; 27(4): 199-207, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23152402
5.
A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.
Eur J Med Chem
; 214: 113229, 2021 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33550186
6.
Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors.
Eur J Med Chem
; 181: 111577, 2019 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31400707
7.
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents.
Eur J Med Chem
; 134: 258-270, 2017 Jul 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28419928
8.
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents.
Sci Rep
; 7: 46356, 2017 04 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28406191
9.
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.
J Med Chem
; 58(7): 3209-22, 2015 Apr 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-25785605
10.
Design, synthesis and biological evaluation of arylcinnamide hybrid derivatives as novel anticancer agents.
Eur J Med Chem
; 81: 394-407, 2014 Jun 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-24858544
11.
Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles.
J Med Chem
; 57(15): 6795-808, 2014 Aug 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-25025853
12.
Anticancer activity of novel hybrid molecules containing 5-benzylidene thiazolidine-2,4-dione.
Eur J Med Chem
; 63: 544-57, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23537942
13.
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4-arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor.
J Med Chem
; 55(17): 7719-35, 2012 Sep 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-22889387
14.
Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.
J Med Chem
; 55(11): 5433-45, 2012 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-22578111
15.
Synthesis and evaluation of 1,5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity.
J Med Chem
; 55(1): 475-88, 2012 Jan 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-22136312
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