Detalles de la búsqueda
1.
In vivo and in vitro metabolite profiling of nirmatrelvir using LC-Q-ToF-MS/MS along with the in silico approaches for prediction of metabolites and their toxicity.
Biomed Chromatogr
; 38(5): e5849, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38403275
2.
Characterization of potential degradation products of brexpiprazole by liquid chromatography/quadrupole-time-of-flight mass spectrometry and nuclear magnetic resonance, and prediction of their physicochemical properties by ADMET Predictor™.
Rapid Commun Mass Spectrom
; 37(1): e9415, 2023 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36226712
3.
Forced degradation study of baricitinib and structural characterization of its degradation impurities by high-resolution mass spectrometry and nuclear magnetic resonance spectroscopy.
Rapid Commun Mass Spectrom
; 37(18): e9605, 2023 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37580847
4.
Development of stability-indicating method for separation and characterization of benidipine forced degradation products using LC-MS/MS.
Biomed Chromatogr
; 37(1): e5517, 2023 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-36200917
5.
Application of online liquid chromatography/quadrupole time-of-flight electrospray ionization tandem mass spectrometry for structural characterization of linagliptin degradation products and related impurities.
Rapid Commun Mass Spectrom
; 34(21): e8874, 2020 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33463844
6.
Preparation and Comparison of Oral Bioavailability for Different Nano-formulations of Olaparib.
AAPS PharmSciTech
; 20(7): 276, 2019 Aug 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31388783
7.
Stability-indicating assay method for acotiamide: Separation, identification and characterization of its hydroxylated and hydrolytic degradation products along with a process-related impurity by ultra-high-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry.
Rapid Commun Mass Spectrom
; 31(21): 1813-1824, 2017 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28836303
8.
Identification of degradation products of saquinavir mesylate by ultra-high-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry and its application to quality control.
Rapid Commun Mass Spectrom
; 31(9): 771-781, 2017 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28233930
9.
Liquid chromatography/tandem mass spectrometry study of forced degradation of azilsartan medoxomil potassium.
Rapid Commun Mass Spectrom
; 29(15): 1437-47, 2015 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26147484
10.
Quality-by-design-based ultra high performance liquid chromatography related substances method development by establishing the proficient design space for sumatriptan and naproxen combination.
J Sep Sci
; 38(19): 3354-62, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26235225
11.
Covalent organic frameworks: spotlight on applications in the pharmaceutical arena.
Bioanalysis
; 2024 Mar 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38445446
12.
Discerning the stability behaviour of mavacamten availing liquid chromatography-mass spectrometry and nuclear magnetic resonance spectroscopy: In silico toxicity and mutagenicity prediction of degradation products.
J Mass Spectrom
; 59(3): e5007, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38445805
13.
LC-HRMS and NMR studies for the characterization of degradation impurities of ubrogepant along with the in silico approaches for the prediction of degradation and toxicity.
J Pharm Biomed Anal
; 243: 116117, 2024 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38522383
14.
Monophasic coamorphous sulpiride: a leap in physicochemical attributes and dual inhibition of GlyT1 and P-glycoprotein, supported by experimental and computational insights.
J Biomol Struct Dyn
; : 1-30, 2024 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38299571
15.
A critical review of Roxadustat formulations, solid state studies, and analytical methodology.
Heliyon
; 9(6): e16595, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-37346363
16.
Insight into in silico prediction and chemical degradation study of osimertinib mesylate by LC-HRMS and NMR: Investigation of a typical case of alkaline pH-mediated oxidative degradation product.
Eur J Mass Spectrom (Chichester)
; 29(2): 123-131, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-36895152
17.
LC-HRMS and NMR studies for characterization of forced degradation impurities of ponatinib, a tyrosine kinase inhibitor, insights into in-silico degradation and toxicity profiles.
J Pharm Biomed Anal
; 227: 115280, 2023 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36773542
18.
In Silico Tools to Thaw the Complexity of the Data: Revolutionizing Drug Research in Drug Metabolism, Pharmacokinetics and Toxicity Prediction.
Curr Drug Metab
; 24(11): 735-755, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38058088
19.
Involvement of Microbiome Gut-Brain Axis in Neuroprotective Effect of Quercetin in Mouse Model of Repeated Mild Traumatic Brain Injury.
Neuromolecular Med
; 25(2): 242-254, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36481824
20.
Structural characterization and in silico toxicity prediction of degradation impurities of roxadustat.
J Pharm Biomed Anal
; 234: 115517, 2023 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37320975